C7LAE2 · C7LAE2_DROME

Function

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site, site.

110251002003004005006007008009001,000
Type
IDPosition(s)Description
Binding site276substrate
Binding site412-416substrate
Binding site448Zn2+ (UniProtKB | ChEBI); catalytic
Active site449Proton acceptor
Binding site452Zn2+ (UniProtKB | ChEBI); catalytic
Binding site471Zn2+ (UniProtKB | ChEBI); catalytic
Site534Transition state stabilizer
Binding site947substrate

GO annotations

AspectTerm
Cellular Componentplasma membrane
Cellular Componentside of membrane
Molecular Functionmetallopeptidase activity
Molecular Functionzinc ion binding
Biological Processproteolysis

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Submitted names
    • LP20836p

Gene names

    • Name
      CG32473-RC

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    C7LAE2

Organism-specific databases

Subcellular Location

Cell membrane
; Lipid-anchor, GPI-anchor

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane35-59Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-26Disordered
Compositional bias12-26Basic and acidic residues
Domain149-340Aminopeptidase N-like N-terminal
Domain376-595Peptidase M1 membrane alanine aminopeptidase
Domain676-994ERAP1-like C-terminal

Sequence similarities

Belongs to the peptidase M1 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,025
  • Mass (Da)
    116,372
  • Last updated
    2009-10-13 v1
  • Checksum
    416E8E195FB84C3F
MYAAKNVRPRSSLSTDDNHRIKDTNRPHKARSNTILTLAAFCVFLLVLCGFLLGALVYVGKNIAEEHQRQQHANASQWALNSTIRTVYVDRDQLLSTKPIISVLSDNRFYTTQVPTSKKSSIMATVAPAVKAASKVLQNLGFRLPKQIKPSKYRLHLRPDLERKNYSGNISISLQVLEPIAFIPVHVKQLNVSTVEVKRLDESGAPLKDITPTLTFAHPEFEYWVTEFEQPLEAGNYSLLLNFTGSLVDRITGMYQSSYLDKLKNRSRSIISTKFEPTYARQAFPCFDEPALKAQFTITVARPSGDEYHVLSNMPVASDYVDGDITEVTFAETVPMSTYLAAFVVSDFQYKETTVEGTSIALKVYAPPAQVEKTQYALDTAAGVMAYYINYFNVSYALPKLDLVAIPDFVSGAMENWGLVTFRETALLYDESTSSSVNKQRVAIVVAHELAHQWFGNLVTMNWWNDLWLNEGFASFLEYKGVKQMHPEWDMDNQFVIEELHPVLTIDATLASHPIVKSIESPAEITEYFDTITYSKGAALVRMLENLVGEEKLRNATTRYLVRHIYSTATTEDYLTAVEEEEGLEFDVKQIMQTWTEQMGLPVVEVEKSGSTYKLTQKRFLANEDDYAAEAEASSFNYRWSIPITYTSSINSEVQSLIFNHNDNEATITLPEEASWIKINTNQVGYYRVNYGSEQWAELISALKNSRETFSTADRAHLLNDANTLAAAGQLNYSVALDLISYLESEQDYVPWSVGTSALATLRNRVYYTDLYTNYTTYARKLLTPIVEKVTFTVAADHLENRLRIKVLSSACSLGHESSLQQAVTLFNQWLASPETRPNPDIRDVVYYYGLQQVNTEAAWDQVWKLYLDESDAQEKLKLMNCLTAVQVPWLLQRYINWAWDESNVRRQDYFTLLGYISTNPVGQSLVWDYVRENWEKLVDRFGINERTLGRLIPTITARFSTETKLEEMQQFFAKYPEAGAGTAARQQALEAVKANIKWLAANKAQVGEWLANYVQQSSVTNRIQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias12-26Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BT099692
EMBL· GenBank· DDBJ
ACV53056.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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