C7GJZ2 · CRP1_YEAS2
- ProteinCruciform DNA-recognizing protein 1
- GeneCRP1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids465 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Cruciform DNA-binding protein which exerts an enhancing effect on the cleavage of cruciform DNA (X-DNA) by endonuclease VII from bacteriophage T4.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleotide-activated protein kinase complex | |
Cellular Component | nucleus | |
Molecular Function | DNA binding | |
Molecular Function | protein kinase binding | |
Biological Process | signal transduction |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameCruciform DNA-recognizing protein 1
- Cleaved into 2 chains
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionC7GJZ2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000409600 | 1-160 | CRP1 short N-terminal subpeptide | ||
Chain | PRO_0000409599 | 1-465 | Cruciform DNA-recognizing protein 1 | ||
Modified residue | 153 | Phosphoserine | |||
Modified residue | 156 | Phosphoserine | |||
Chain | PRO_0000409601 | 161-465 | CRP1 short C-terminal subpeptide | ||
Modified residue | 182 | Phosphothreonine | |||
Modified residue | 271 | Phosphoserine | |||
Modified residue | 295 | Phosphothreonine | |||
Modified residue | 319 | Phosphoserine | |||
Modified residue | 343 | Phosphoserine | |||
Modified residue | 366 | Phosphothreonine | |||
Modified residue | 394 | Phosphoserine | |||
Modified residue | 440 | Phosphoserine | |||
Post-translational modification
Cleaved in the vicinity of position 160 to give an X-DNA-binding N-terminal subpeptide and a non-DNA-binding C-terminal subpeptide.
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 107-227 | Disordered | |||
Compositional bias | 129-147 | Basic residues | |||
Region | 160-161 | X-DNA-binding | |||
Compositional bias | 169-185 | Polar residues | |||
Region | 247-275 | Disordered | |||
Region | 305-465 | Disordered | |||
Compositional bias | 334-367 | Basic and acidic residues | |||
Compositional bias | 388-432 | Basic and acidic residues | |||
Sequence similarities
Belongs to the CRP1/MDG1 family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length465
- Mass (Da)51,124
- Last updated2009-10-13 v1
- Checksum1E9FAD19F930B9A4
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 129-147 | Basic residues | |||
Compositional bias | 169-185 | Polar residues | |||
Compositional bias | 334-367 | Basic and acidic residues | |||
Compositional bias | 388-432 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ACFL01000017 EMBL· GenBank· DDBJ | EEU08899.1 EMBL· GenBank· DDBJ | Genomic DNA |