SOX9 and the switch hitting genes.CategoryFunctionSourceMGI: 98371PubMedEurope PMCNat Genet 9:1-2 (1995)Mapped to23
The <i>Odad3</i> Gene Is Necessary for Spermatozoa Development and Male Fertility in Mice.Pasquini M., Chiani F., Gambadoro A., Di Pietro C., Paoletti R., Orsini T., Putti S., Scavizzi F., La Sala G., Ermakova O.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCCells 13:1053-1053 (2024)Mapped to25
The IFITM5 mutation in osteogenesis imperfecta type V is associated with an ERK/SOX9-dependent osteoprogenitor differentiation defect.Marom R., Song I.W., Busse E.C., Washington M.E., Berrier A.S., Rossi V.C., Ortinau L., Jeong Y., Jiang M.M.[...], Lee B.H.View abstractAnnotationThe IFITM5 mutation in osteogenesis imperfecta type V is associated with an ERK/SOX9-dependent osteoprogenitor differentiation defect.CategoryFunctionSourceGeneRif: 20682PubMedEurope PMCJ Clin Invest 134:e170369-e170369 (2024)Mapped to23
Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development.Ichiyama-Kobayashi S., Hata K., Wakamori K., Takahata Y., Murakami T., Yamanaka H., Takano H., Yao R., Uzawa N., Nishimura R.View abstractAnnotationChromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development.CategoryFunctionSourceGeneRif: 20682PubMedEurope PMCJCI Insight 9:e175486-e175486 (2024)Mapped to22
Conditional disruption of Nr5a1 directed by Sox9-Cre impairs adrenal development.Tagami A., Ikeda Y., Ishizuka K., Maekawa M.View abstractAnnotationConditional disruption of Nr5a1 directed by Sox9-Cre impairs adrenal development.CategoryFunctionSourceGeneRif: 20682, MGI: 98371PubMedEurope PMCSci Rep 14:12297-12297 (2024)Mapped to44
CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair.Hassan D., Chen J.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCNat Commun 15:4148-4148 (2024)Mapped to33
Downregulation of SOX9 expression in developing entheses adjacent to intramembranous bone.Kitamura A., Yamamoto M., Hirouchi H., Watanabe G., Taniguchi S., Sekiya S., Ishizuka S., Jeong J., Higa K.[...], Abe S.View abstractAnnotationDownregulation of SOX9 expression in developing entheses adjacent to intramembranous bone.CategoryFunctionSourceGeneRif: 20682, MGI: 98371PubMedEurope PMCPLoS One 19:e0301080-e0301080 (2024)Mapped to44
FOXL2 interaction with different binding partners regulates the dynamics of ovarian development.Migale R., Neumann M., Mitter R., Rafiee M.R., Wood S., Olsen J., Lovell-Badge R.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCSci Adv 10:eadl0788-eadl0788 (2024)Mapped to37
Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9.Trogisch F.A., Abouissa A., Keles M., Birke A., Fuhrmann M., Dittrich G.M., Weinzierl N., Wink E., Cordero J.[...], Heineke J.View abstractAnnotationEndothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9.CategoryFunctionSourceGeneRif: 20682PubMedEurope PMCSci Transl Med 16:eabq4581-eabq4581 (2024)Mapped to22
Inefficient Sox9 upregulation and absence of Rspo1 repression lead to sex reversal in the B6.XYTIR mouse gonad†.Cao J., El Mansouri F., Reynoso S., Liu Z., Zhu J., Taketo T.View abstractAnnotationInefficient Sox9 upregulation and absence of Rspo1 repression lead to sex reversal in the B6.XYTIR mouse gonaddagger.CategoryFunctionSourceGeneRif: 20682PubMedEurope PMCBiol Reprod 110:985-999 (2024)Mapped to24
Skeletal growth is enhanced by a shared role for SOX8 and SOX9 in promoting reserve chondrocyte commitment to columnar proliferation.Molin A.N., Contentin R., Angelozzi M., Karvande A., Kc R., Haseeb A., Voskamp C., de Charleroy C., Lefebvre V.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCProc Natl Acad Sci U S A 121:e2316969121-e2316969121 (2024)Mapped to44
GITRL impairs hepatocyte repopulation by liver progenitor cells to aggravate inflammation and fibrosis by GITR<sup>+</sup>CD8<sup>+</sup> T lymphocytes in CDE Mice.Li L., He Y., Liu K., Liu L., Shan S., Liu H., Ren J., Sun S., Wang M.[...], Wang P.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCCell Death Dis 15:114-114 (2024)Mapped to24
A PTHrP Gradient Drives Mandibular Condylar Chondrogenesis via Runx2.Tsutsumi-Arai C., Arai Y., Tran A., Salinas M., Nakai Y., Orikasa S., Ono W., Ono N.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCJ Dent Res 103:91-100 (2024)Mapped to48
Single-cell, whole-embryo phenotyping of mammalian developmental disorders.Huang X., Henck J., Qiu C., Sreenivasan V.K.A., Balachandran S., Amarie O.V., Hrabe de Angelis M., Behncke R.Y., Chan W.L.[...], Spielmann M.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCNature 623:772-781 (2023)Mapped to37
A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression.Liu Y., John P., Nishitani K., Cui J., Nishimura C.D., Christin J.R., Couturier N., Ren X., Wei Y.[...], Guo W.View abstractAnnotationA SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression.CategoryFunctionSourceGeneRif: 20682, MGI: 98371PubMedEurope PMCDev Cell 58:2700-2717.e12 (2023)Mapped to26
Development of the arterial roots and ventricular outflow tracts.Anderson R.H., Lamers W.H., Hikspoors J.P.J.M., Mohun T.J., Bamforth S.D., Chaudhry B., Eley L., Kerwin J., Crosier M., Henderson D.J.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCJ Anat 244:497-513 (2024)Mapped to35
Altered Sox9 and FGF signaling gene expression in Aga2 OI mice negatively affects linear growth.Zieba J., Nevarez L., Wachtell D., Martin J.H., Kot A., Wong S., Cohn D.H., Krakow D.View abstractAnnotationAltered Sox9 and FGF signaling gene expression in Aga2 OI mice negatively affects linear growth.CategoryFunctionSourceGeneRif: 20682, MGI: 98371PubMedEurope PMCJCI Insight 8:e171984-e171984 (2023)Mapped to22
EGR1 Promotes Ovarian Hyperstimulation Syndrome Through Upregulation of SOX9 Expression.Wang H., Chen W., Huang Y., Sun Y., Liu Y., Zhu Y., Lu Z.View abstractAnnotationEGR1 Promotes Ovarian Hyperstimulation Syndrome Through Upregulation of SOX9 Expression.CategoryFunctionSourceGeneRif: 20682PubMedEurope PMCCell Transplant 32:9636897231193073-9636897231193073 (2023)Mapped to46
Sox9 Inhibits Cochlear Hair Cell Fate by Upregulating Hey1 and HeyL Antagonists of Atoh1.Veithen M., Huyghe A., Van Den Ackerveken P., Fukada S.I., Kokubo H., Breuskin I., Nguyen L., Delacroix L., Malgrange B.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCCells 12:2148-2148 (2023)Mapped to39
Durable alveolar engraftment of PSC-derived lung epithelial cells into immunocompetent mice.Herriges M.J., Yampolskaya M., Thapa B.R., Lindstrom-Vautrin J., Wang F., Huang J., Na C.L., Ma L., Montminy M.M.[...], Kotton D.N.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCCell Stem Cell 30:1217-1234.e7 (2023)Mapped to32
Thymic epithelial cell fate and potency in early organogenesis assessed by single cell transcriptional and functional analysis.Farley A.M., Chengrui A., Palmer S., Liu D., Kousa A.I., Rouse P., Major V., Sweetman J., Morys J.[...], Blackburn C.C.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCFront Immunol 14:1202163-1202163 (2023)Mapped to28
PRC1 suppresses a female gene regulatory network to ensure testicular differentiation.Maezawa S., Yukawa M., Hasegawa K., Sugiyama R., Iizuka M., Hu M., Sakashita A., Vidal M., Koseki H.[...], Namekawa S.H.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCCell Death Dis 14:501-501 (2023)Mapped to44
Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor.Schoultz E., Liang S., Carlsson T., Filges S., Stahlberg A., Fagman H., Wiel C., Sayin V., Nilsson M.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCiScience 26:107071-107071 (2023)Mapped to36
Induction of kidney-related gene programs through co-option of SALL1 in mole ovotestes.Schindler M., Osterwalder M., Harabula I., Wittler L., Tzika A.C., Dechmann D.K.N., Vingron M., Visel A., Haas S.A., Real F.M.View abstractCategoryFunctionSourceMGI: 98371PubMedEurope PMCDevelopment 150:dev201562-dev201562 (2023)Mapped to36
The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates.Yang Y., Gomez N., Infarinato N., Adam R.C., Sribour M., Baek I., Laurin M., Fuchs E.View abstractAnnotationThe pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates.CategoryFunctionSourceGeneRif: 20682PubMedEurope PMCNat Cell Biol 25:1185-1195 (2023)Mapped to22