C6KTF7 · C6KTF7_PLAF7

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenthost cell plasma membrane
Cellular Componentinfected host cell surface knob
Cellular Componentmembrane
Molecular Functioncell adhesion molecule binding
Molecular Functionhost cell surface receptor binding
Biological Processadhesion of symbiont to microvasculature
Biological Processantigenic variation
Biological Processcell-cell adhesion
Biological Processmodulation by symbiont of host erythrocyte aggregation

Names & Taxonomy

Protein names

  • Submitted names
    • Erythrocyte membrane protein 1, PfEMP1

Gene names

    • ORF names
      PF3D7_0632500

Organism names

  • Taxonomic identifier
  • Strain
    • Isolate 3D7
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Haemosporida > Plasmodiidae > Plasmodium > Plasmodium (Laverania)

Accessions

  • Primary accession
    C6KTF7

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)183PTMeXchangePhosphoserine

Proteomic databases

Structure

3D structure databases

Family & Domains

Features

Showing features for domain, region, compositional bias, coiled coil.

TypeIDPosition(s)Description
Domain15-50Plasmodium falciparum erythrocyte membrane protein-1 N-terminal segment
Domain114-310Duffy-antigen binding
Domain314-472Duffy-binding-like
Region469-499Disordered
Domain652-810Duffy-binding-like
Domain938-1112Duffy-antigen binding
Domain1360-1539Duffy-antigen binding
Compositional bias1732-1758Polar residues
Region1732-1760Disordered
Domain1761-1933Duffy-antigen binding
Domain1974-2121Duffy-binding-like
Domain2223-2369Duffy-binding-like
Region2368-2420Disordered
Domain2464-2613Duffy-antigen binding
Coiled coil2686-2713
Domain2816-2951Duffy-antigen binding
Domain3143-3286Duffy-antigen binding
Region3411-3431Disordered
Domain3444-3954Plasmodium falciparum erythrocyte membrane protein 1 acidic terminal segment
Region3558-3589Disordered
Region3608-3627Disordered
Region3800-3830Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    3,954
  • Mass (Da)
    456,918
  • Last updated
    2009-09-01 v1
  • Checksum
    374626667C675F8B
MGPPGGSGGSTLDESVKDLFDRIGKEVHDQVEKEANQYKEALKGDLSSATFPTGRRHEKPQSESCKLNYIYDTNVTSGGGKENPCYGRQGVRFSDTKGAKCYSYKIEDNDSSIGFCAPYRRLHLCVQNLEQIKPDQITSTHNLLVDVLLAAKYEGQSITQDYPKYQATYDDSPSKMCTMLARSFADIGDIVRGKDLFLGTNEEKKPLEENLKEIFKKIYENLGIQEKNHYNDTPDYYKLREDWWIANRDQVWKAITCNAGGYSYFRKTCGGDNEKNSTLASNKCRCKDEKGEHDTDQVPTYFDYVPQYLRWFEEWAEDFCRKKKIKVENVKKSCRGEDKESKDRYCSRNGYDCEKTKRAIGKLRYGKQCISCLYGCNPYVDWIEKQKEQFDKQKKIYDKEIKKYENGASSSSRKTRAASTTNYEEYEKKFYEELNKSEYSDVNAFLEKLSKEDVCTKVQDDKGGRISFENVKSSSASGGAAGTSSTSGGGTSGDSGTNNENEGTFYRSKYCQPCPPCGVERNVNDWKEKHKIQECKSINLYKPNEYAKPTNITILKSGEGHEDIETKLKAFCDKKDGTGSGDCGGNSDPSLCEPWQCYEEKDIEKHGDVDDDDADGNPLNAGGLCILKNEKHVSETNSQIEPDQFQKTFHDFFYYWVAHMLKDSIHWKKKLQRCLEKKNGNTCKKNNCKDNCGCFEKWVAQKKEQEWDPIKQQFRKQDFGKQELILGQIRYDYVLDELLKKDELLTSIKEGYGDANEIKHIKALLEDEENEETQEEETAGADNQKKNTIDWLIQHEEDDAELCLEIHEDEEEGGGNDECDDDHEEEVYVSNPCATPSGSYPSLANKVAQLMHHKAKTQLAIRAGRSLLRANASKGEYKHEGNPDDFKKEKLCEITAKHSNDSRRDGEPCKGKDGNNERFKIGTEWKIGEKVETSYKDVFLPPRRQHMCTSNLENLDVDSVTENDKASHSLLGDVQLAAKTDAAEIIKRYKDQNNIQLTDPIQQKDQEAMCRAIRYSFADLGDIIRGRDMWNKDSGSTEMEKHLISIFEKINEKLPEKEQKKYSNDGKYLDLRKDWWEANRYKVWKAMKCATKNSKIPCSGIPIEDYIPQRLRWMTEWAEWFCKEQSQAYETLQDQCGKCTGPNKDNCTRDNNDCNTCTKACEEYEQKIKKWADQWKVISKKYEELYLQAKTAFARTAFPDDDPDYQQVVEFFKELQKEINRSASQRSKRSIDVTNTDPTLTSPYSSAAGYIHQEIGNVGCNVQTQFCEKKNGVIPTTGSGTNNKNYAFKNTPKDHDEACECESRPQVPPKKKEDEEDVCEKVKGLLKGKDGETTEINGCKPKGNGNTWNCSNQIDDSHKGACMPPRRQSLCIHNLKESNETGTEQQLREAFINCAAIETFWLWYKYKKDKNVDAEKKLEQGEIPSEFLRSMIYTFGDYRDLCLNTDISAKKDPIKIVKNNIQKVFNRNNGPHKEGDKEKRKKFWETNKNDIWQGMLCALEKIANNKKTLTETYNYSLVKFSGNNSTTLEDFAKTPQFLRWFTEWGDDFCQQQKEQLVTLQEACPNGICEQSEEEKKKCKSACEKYQAFIEKWKGYYDKQSKKYFYDISTGMYKDNSSAKDDVTVSSYAYEYLNKSLKKLCPDGSCSCMEQRSQQHNEDSSDALETHNSIMPQSLDKEPKEVKGRCKCPDPPKPCDIVKDLFENKDDNKFTEACSTKYKNGKEKYTQWKCINDSSNTTRSSPPAPVASSTLSTSPEAGASATCIPPRRQQMYIQPLQSLSGNESQVELRRIFIEMAAIETFFQWHKFKKEKVREIKEKDEIDGKISLFGQDDTSIEENLQKQLKNGTIPDDFKRQMFYTFGDYKDILFGKYIGIDMGTVKTNIGRVFNNGGNKSDEEREKWWKNHGPSIWNGMLCGLSYDTKTKHNIQGVYTQLTDPSKNNMYEKVTFPSKTGPSVNTKLEQFARRPTYFRWLEEWGEEFCKKRTDKLKKLEKECRGVNYSGYNKYCSGDGYHCDDEKGTYNSINANLNCRDCMKECRNYKTWIVKKKNEYDKQKSKYVNEHENVISFLNKQSYKQLYENIKPYSSAADFFTSLNHCKPDKANDDKNNKLNFKNPHETFSPSTYCKACPLNGVICRGRSQCAANSENNLTNLGESTDFDILINDAAIHDNDNEIKKGCPTYEMYKDLRKQKWICQKKTGEVHQCKLNNAADSKYYDNKFPFNILFHRWITDFIQYYNKSKEKIKPCTNDVNSCKQGCKGNCDCVDKWLKNKSTEWEIIKKYYKENFGNTNEHIAYAIKIFLQEGLFDSDYKRAQEVIDQNEWEQLWGCTGDNLKDVKDQKAENCNKGDFITNLISKLQDKITSCQNKHNPNGKTACDEIPPHSDEEETSLLDDDTSTQEKMSPDFCPSDMPEKPKTDSDILCDDKKEPKCGNFRTLFKTSTSKTKTNLIGLEAHNHRAGRFYPNVYISPRAHQLYLEPLKDLKENNTDKNELIKAFTKCAYNEGKCLYEYYSKNKATLGKNGSALSNDEVKTYTLEAMERSYADYGTIVKEDILWDYEDKKKIDPKIMNFAKNHNISTTKTIVSSLDDDDVKRQKLWESIRIDVWKAMICGYKDAIGGDMNSLPNDVDLCTLPTTDDEYSFLRWFVEWGQNFCIRHEKELKQLNEECARGTCDGTDEEKKKKCEKACKNYREFLNNFKKQYENQKKEYEIIKSSYPKYEKKDAFTFLKDKCNSNYSCFENKTEISVLKMFEHPPDDVKDECDCKTSKAHDDKVNDLDKCPNNINNNKNICNKYKKRRICGDLKYSNSLDHWFGTNTLIPPRRRHLCLRNIIIKKNYRKGDISKFKDDLFYAAASEAKFLFNNYENKNESLQAIKYTFADIGDIIKGNDMMDDMTYKKIKGKLEKVLDKTGNNPETPEKWWEQNKKHVWEAMLCGYKLAGGEIKPNDCNIPTEESTHQFLRWLTEWGTQYCKEKQQLKLNMQIPCMTHFDKYGIIENRIDVHPNCLQGLGKYEIWSNNRIPDWERLSSKFNEVKGTMNENVKKLTAYEYLKQNCSKCICSFKDIEQTHKKSKDEGYHIYEDILDKAQIPSFLEDTAYRYKGLNPECPEDIECSQYGNIPCRGVSHDDDNDWNSSFVKDNKTTNLGVLVPPRRRHLCLRIDVNKFLRLRNDINNLKTFICKSAFAEAKRLKKVYKDDNSKLHQAMKYSFSDIGSVVKGNDMMESPTSDNIAKIFRGMKYTEINRETWWDLNKYHVWESMLCGYREAGGDTKKSENCRFPDIERVPQFLRWFQEWTEIFCIKRKTLYDKMVTECQKAECDTSNGTVKETKCTKACEEYKSYVLSKKKEYYIQKDKYDNQFKKVLNNKDAEEFLNVHCLSEYFKDETRWKNPYESIADKALKGKCDCKKMIPTTPEVKPKKPAVPEAKKPEVEPLPSDEPFNRDILEKTIPFGVALALGSIAFLFLKKKTQAPVDLFSVINIPKGDHDIPTLKSSNRYIPYVSDRYKGKTYIYMEGDSDSGHYYEDTTDITSSESEYEELDINDIYPYKSPKYKTLIEVVLEPSGNNTPTSDTPSDTQNDIPSGDTPNNKLTDNEWNTLKDEFISQYIQSEQPNDVPNDYTSGNSSTNTNITTTSRHNVEEKPFIMSIHDRNLYTGEEYNYDMSTNSGNNDLYNGKNNLYSGQNNVYSGIDPTSDNRGPYSDKNDRISDNHHPYSGIDLINDTLSGNAHIDIYDELLKRKENELFGTNHVKHTSTHSVAKHTNSDPIHNQLNLFHTWLDRHRDMCEKWNTKEELLDKLNEQWNKDNNNSGNINPSGNTPPTSDIPSGKLSDIPSDNNIHSDIPYVLNTDVSIQIDMNNPKTTNEFTYVDSNPNQVDDTYVDSNPDNSSMDTILEDLDKPFNEPYYYDMYDDDIYYDVHDHDTSTVDTNAMDVPSKVQIEMDVNTKLVKEKYPISDVWDI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1732-1758Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL844505
EMBL· GenBank· DDBJ
CAG25137.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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