C6E7E7 · QUEC_GEOSM
- Protein7-cyano-7-deazaguanine synthase
- GenequeC
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids225 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ0).
Catalytic activity
- 7-carboxy-7-deazaguanine + ATP + NH4+ = 7-cyano-7-deazaguanine + ADP + H+ + H2O + phosphate
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | ligase activity, forming carbon-nitrogen bonds | |
Molecular Function | zinc ion binding | |
Biological Process | queuosine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name7-cyano-7-deazaguanine synthase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Desulfuromonadia > Geobacterales > Geobacteraceae > Geobacter
Accessions
- Primary accessionC6E7E7
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000215792 | 1-225 | 7-cyano-7-deazaguanine synthase | |||
Sequence: MQKKAVILYSGGLDSTTCLAIAKKQGFAPYALSFSYGQRHQQELEVAKLNARPMGAVDHLLVEFDLRKMGGSALTSDIEVPKEGVGEEIPVTYVPARNTIFLSFALGWAETLDCFDIFIGVNALDYSGYPDCRPEFISAYETMANLATKAGVEGKRLQIHTPLISLTKAEIIQKGISLGVDYSKTHSCYDPAEDGAACGRCDSCRLRLKGFAEAGVTDPVRYQKL |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length225
- Mass (Da)24,526
- Last updated2009-09-01 v1
- Checksum363E2749378DDF45
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001661 EMBL· GenBank· DDBJ | ACT19807.1 EMBL· GenBank· DDBJ | Genomic DNA |