C5PHC9 · C5PHC9_COCP7
- ProteinDNA 3'-5' helicase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1310 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
Cofactor
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chromosome | |
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | 3'-5' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | DNA binding | |
Molecular Function | four-way junction helicase activity | |
Molecular Function | hydrolase activity | |
Molecular Function | isomerase activity | |
Molecular Function | metal ion binding | |
Biological Process | DNA unwinding involved in DNA replication | |
Biological Process | double-strand break repair via homologous recombination |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA 3'-5' helicase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Onygenales > Onygenaceae > Coccidioides
Accessions
- Primary accessionC5PHC9
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-20 | Polar residues | ||||
Sequence: MNSWSQKTPKHSSPLKTRLI | ||||||
Region | 1-64 | Disordered | ||||
Sequence: MNSWSQKTPKHSSPLKTRLITISDSEEEASDAIWEAEPEGRARTSLSSAELHPRVQHKKNQSAL | ||||||
Region | 308-340 | Disordered | ||||
Sequence: SVTRAGSTRPFEDSFDAPWRNSPGVSPSNKPYQ | ||||||
Domain | 459-640 | Helicase ATP-binding | ||||
Sequence: INATLSGKDAFVLMPTGGGKSLCYQLPSVVQSGRTRGVTVVISPLLSLMDDQVGQLRSLSVKAHFINGSLKAAERRQILEYLQDPRVEDQIQLLYVTPEMVNKSQAMLDTLRQLHRRKKFARLVIDEAHCVSQWGHDFRPDYKELGDFRRHFPGVPLMALTATATQNVKVDVIHNLGMDGCE | ||||||
Domain | 660-815 | Helicase C-terminal | ||||
Sequence: NHEDVLENIAKIIDFHYGKTGIIYCLSRKNCEKVAKDLCTKYHVKATHYHAGMAPDDRIRVQREWQDGKHNVIVATIAFGMGIDKPDVRFVIHHTIPKSLEGYYQETGRAGRDGKRSECFLFYGYRDVVAIRKIIDDEKNGRKDRQQKDRQHQMLQ | ||||||
Region | 1032-1051 | Disordered | ||||
Sequence: EDDLEEENESDSDGFEPIRQ | ||||||
Domain | 1077-1160 | HRDC | ||||
Sequence: TQLQTMILDEFLLMAKKECQAIMLKKNLRSQPFPDRVLREMGIRFPKNKSQLLRIPDIDPEKVDLYGDKFLKLVDMSKQRYDEF | ||||||
Region | 1169-1310 | Disordered | ||||
Sequence: DREELPVPDPNHNVVTIISDDERDDDDYREYPNPSEETGATKSRYFSRPSQSSTSFRSRMTEYQSSQKNNSSPGKPRTSRKGSFSSKSDRAPRQARKDKSFSSGSGKKARSGQWRSKSSSSRSKHAPKSKASNSLAIGMMPT | ||||||
Compositional bias | 1204-1249 | Polar residues | ||||
Sequence: EETGATKSRYFSRPSQSSTSFRSRMTEYQSSQKNNSSPGKPRTSRK | ||||||
Compositional bias | 1250-1272 | Basic and acidic residues | ||||
Sequence: GSFSSKSDRAPRQARKDKSFSSG | ||||||
Compositional bias | 1273-1298 | Polar residues | ||||
Sequence: SGKKARSGQWRSKSSSSRSKHAPKSK |
Sequence similarities
Belongs to the helicase family. RecQ subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,310
- Mass (Da)148,520
- Last updated2009-09-01 v1
- Checksum61BB5AB916AF2DD9
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-20 | Polar residues | ||||
Sequence: MNSWSQKTPKHSSPLKTRLI | ||||||
Compositional bias | 1204-1249 | Polar residues | ||||
Sequence: EETGATKSRYFSRPSQSSTSFRSRMTEYQSSQKNNSSPGKPRTSRK | ||||||
Compositional bias | 1250-1272 | Basic and acidic residues | ||||
Sequence: GSFSSKSDRAPRQARKDKSFSSG | ||||||
Compositional bias | 1273-1298 | Polar residues | ||||
Sequence: SGKKARSGQWRSKSSSSRSKHAPKSK |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ACFW01000049 EMBL· GenBank· DDBJ | EER23932.1 EMBL· GenBank· DDBJ | Genomic DNA |