C5P6P5 · C5P6P5_COCP7

Function

function

Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site133L-glutamate (UniProtKB | ChEBI)
Active site409Nucleophile
Binding site427-429L-glutamate (UniProtKB | ChEBI)
Binding site451L-glutamate (UniProtKB | ChEBI)
Binding site479-480L-glutamate (UniProtKB | ChEBI)
Binding site502L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionglutathione hydrolase activity
Molecular Functionleukotriene C4 gamma-glutamyl transferase activity
Biological Processglutathione catabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione hydrolase
  • EC number
  • Alternative names
    • Gamma-glutamyltransferase
    • Gamma-glutamyltranspeptidase

Gene names

    • ORF names
      CPC735_024310

Organism names

Accessions

  • Primary accession
    C5P6P5

Proteomes

Organism-specific databases

Subcellular Location

Family & Domains

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    599
  • Mass (Da)
    65,187
  • Last updated
    2009-09-01 v1
  • Checksum
    53B9E8EB48FE5D14
MLRSLLIMISPAVLALCVGFYIFSTFADLSCATPIRRHSSYPWLNQGSGRPDSGQEVDAWARQDDRLGAVASESSICSGFGVDMLKLGGNAADAMVATVFCVGVVGMYHSGIGGGGFMLIRSPDDTYEFVDFRETAPAAAFQDMYNNNTDASIFGGLASGVPGEVRGLEYLHKKHGLLPWRLVMQPAIHTARYGFPVTEDLVRYMREATEGKEDFLTNNPTWALDFAPNGTRLGLGDTITRKRYANTLETIANYGADAFYSGAIAETIIQALHAQNGTMTLEDLKNYTVDIKETAQIDYRGFKVTSTSAPSSGAILLSTLNILEGYDDFFAQGTTDLSTHRLDEAIRFAYGQRTHMGDPRFVEGLGEFQQDILNKSVSAQIRGKILDERTQNISAYEPSGFEILETPGTSHISSADRNGLAISLTTTVNLYFGSKVMVPETGIIMNNEMNDFSIPGSDNAFGYRPSPANYIRPGKRPLSSICPTIVTHPNGTMYFITGAAGGSRIITSTLQSVINVLDRHMTAPQALAEPRLHDQLVPNLTEVEWSFDNSTVEFLIDRGHNITRVEHASSTVQSIRVLSNGTFEAAGEPRQLNSGGLAI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ACFW01000025
EMBL· GenBank· DDBJ
EER27095.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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