C5E826 · C5E826_BIFLI

Function

function

Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO3- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO3- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site117ATP (UniProtKB | ChEBI)
Binding site157ATP (UniProtKB | ChEBI)
Binding site162-168ATP (UniProtKB | ChEBI)
Binding site196-199ATP (UniProtKB | ChEBI)
Binding site204ATP (UniProtKB | ChEBI)
Binding site226ATP (UniProtKB | ChEBI)
Binding site280-281ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function5-(carboxyamino)imidazole ribonucleotide synthase activity
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionphosphoribosylaminoimidazole carboxylase activity
Biological Process'de novo' IMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    N5-carboxyaminoimidazole ribonucleotide synthase
  • EC number
  • Short names
    N5-CAIR synthase
  • Alternative names
    • 5-(carboxyamino)imidazole ribonucleotide synthetase

Gene names

    • Name
      purK
    • ORF names
      BLIG_00119

Organism names

Accessions

  • Primary accession
    C5E826

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain121-310ATP-grasp

Sequence similarities

Belongs to the PurK/PurT family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    392
  • Mass (Da)
    42,777
  • Last updated
    2009-07-28 v1
  • Checksum
    7B2E2BFF05182FF4
MPSLSEETGGRVSMLMPGSTIGIIGGGQLGRMMALSARYMGFRVGVLDPTPNCPTGQVADFQITAEYDDKTAIHDLAVQSDVLTYEFENVDAGAIDEVRGITATPQGTDLLRVTQHRVREKQFINDHGTATAPWRAVNNFDELDAALGDIHYPAVLKTVSGGYDGHGQLVLRSDADLEKIRSRSDRGGGFPPSILEGFVDFAFEASILVSGNGKDFVTFPIVRNEHRNNILHMTIAPAEVSEHVAREAHELAIRLAKGFELAGTLAIELFITKDDQVIVNELAPRPHNSGHYTIEACSMDQFDAHIRGIAGWPLPKPKLLSPAVMVNVLGQHVEPTRALIATHPEWNVHDYGKAEVRHDRKMGHITVLTDDPAKTVADLEATGCWDDLKKKA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DS990238
EMBL· GenBank· DDBJ
EEQ54170.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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