C4XST3 · G6PI_SOLM1
- ProteinGlucose-6-phosphate isomerase
- Genepgi
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids549 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
Catalytic activity
- alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 353 | Proton donor | ||||
Sequence: E | ||||||
Active site | 384 | |||||
Sequence: H | ||||||
Active site | 512 | |||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | carbohydrate derivative binding | |
Molecular Function | glucose-6-phosphate isomerase activity | |
Molecular Function | monosaccharide binding | |
Biological Process | gluconeogenesis | |
Biological Process | glucose 6-phosphate metabolic process | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlucose-6-phosphate isomerase
- EC number
- Short namesGPI
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Desulfovibrionia > Desulfovibrionales > Desulfovibrionaceae > Solidesulfovibrio
Accessions
- Primary accessionC4XST3
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000206363 | 1-549 | Glucose-6-phosphate isomerase | |||
Sequence: MAQLTEHPAHSALVAHHERVRDLHMRDLFAADSGRFDKLSLRLGDILFDYSKNRVTDETLGLLFDLARQAGVEARRDAMFAGEKINRTENRAVLHVALRNRANRPILVDGHDVMPDVNKVLNQMRIFCGRVHSGQWKGYSGKAITDVVNIGIGGSDLGPQMASLALAQYAVPGITSHFVSNVDGAHMVETLQRVSPETTLFIIASKTFTTLETMANAHDARDWFLAQAGDEAAVAKHFVALSTNAEAVAAFGIDTANMFAFWDWVGGRYSLWSAIGLSIALAVGFDNFEAMLEGAFLADEHFRSAPLERNIPVVMGLLGIWYNNYFGAQTQAILPYDQHLTRFAAYFQQGDMESNGKSVTNDGRFVDYTTGPIIWGEPGTNGQHAFYQLIHQGRKLIPCDFLAAAITRTPLGRHQDMLLSNFFAQTEALMKGKTVDEARAELADKVLGEAQLELLSKAKSFTGNRPTNSFLYRVLDPKTLGTLIALYEHKIFVQGTIWDINSYDQMGVELGKVLAGTILKELENDAPVASHDCSTNGLVNYYKELRLGD |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length549
- Mass (Da)60,645
- Last updated2009-07-28 v1
- Checksum16530E7C3E6C4A15
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP010904 EMBL· GenBank· DDBJ | BAH75775.1 EMBL· GenBank· DDBJ | Genomic DNA |