C4F7X2 · C4F7X2_9ACTN
- ProteinTyrosine recombinase XerC
- GenexerC
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids333 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 181 | ||||
Active site | 205 | ||||
Active site | 279 | ||||
Active site | 282 | ||||
Active site | 305 | ||||
Active site | 314 | O-(3'-phospho-DNA)-tyrosine intermediate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | DNA binding | |
Molecular Function | tyrosine-based site-specific recombinase activity | |
Biological Process | cell division | |
Biological Process | chromosome segregation | |
Biological Process | DNA transposition |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameTyrosine recombinase XerC
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Coriobacteriia > Coriobacteriales > Coriobacteriaceae > Collinsella
Accessions
- Primary accessionC4F7X2
Proteomes
Subcellular Location
Interaction
Subunit
Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-22 | Disordered | |||
Domain | 34-120 | Core-binding (CB) | |||
Domain | 141-327 | Tyr recombinase | |||
Sequence similarities
Belongs to the 'phage' integrase family. XerC subfamily.
Belongs to the 'phage' integrase family. XerD subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length333
- Mass (Da)37,120
- Last updated2009-07-07 v1
- ChecksumBAF320BD5517214A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ABXH02000003 EMBL· GenBank· DDBJ | EEP45090.1 EMBL· GenBank· DDBJ | Genomic DNA |