C3YMS4 · C3YMS4_BRAFL
- ProteinAcyl-coenzyme A oxidase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids660 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 = (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- octadecanoyl-CoA + O2 = (2E)-octadecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- octanoyl-CoA + O2 = (2E)-octenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- tetradecanoyl-CoA + O2 = (2E)-tetradecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- decanoyl-CoA + O2 = (2E)-decenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2This reaction proceeds in the forward direction.
- hexanoyl-CoA + O2 = (2E)-hexenoyl-CoA + H2O2This reaction proceeds in the forward direction.
Cofactor
Pathway
Lipid metabolism; peroxisomal fatty acid beta-oxidation.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 140 | FAD (UniProtKB | ChEBI) | |||
Binding site | 179 | FAD (UniProtKB | ChEBI) | |||
Active site | 422 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | peroxisome | |
Molecular Function | FAD binding | |
Molecular Function | fatty acid binding | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | palmitoyl-CoA oxidase activity | |
Biological Process | fatty acid beta-oxidation using acyl-CoA oxidase | |
Biological Process | lipid homeostasis | |
Biological Process | very long-chain fatty acid metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameAcyl-coenzyme A oxidase
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Cephalochordata > Leptocardii > Amphioxiformes > Branchiostomatidae > Branchiostoma
Accessions
- Primary accessionC3YMS4
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 260-282 | Helical | |||
Transmembrane | 332-354 | Helical | |||
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 15-134 | Acyl-coenzyme A oxidase N-terminal | |||
Domain | 137-246 | Acyl-CoA oxidase/dehydrogenase middle | |||
Domain | 315-437 | Acyl-CoA oxidase C-alpha1 | |||
Domain | 473-653 | Acyl-CoA oxidase C-terminal | |||
Sequence similarities
Belongs to the acyl-CoA oxidase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length660
- Mass (Da)73,952
- Last updated2009-07-28 v1
- MD5 ChecksumC1A7C512E063986B19AC3BE577AB3C68
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GG666531 EMBL· GenBank· DDBJ | EEN58415.1 EMBL· GenBank· DDBJ | Genomic DNA |