C3YMS4 · C3YMS4_BRAFL

Function

Catalytic activity

  • (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 = (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2
    This reaction proceeds in the forward direction.
  • (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2
    This reaction proceeds in the forward direction.
  • octadecanoyl-CoA + O2 = (2E)-octadecenoyl-CoA + H2O2
    This reaction proceeds in the forward direction.
  • octanoyl-CoA + O2 = (2E)-octenoyl-CoA + H2O2
    This reaction proceeds in the forward direction.
  • tetradecanoyl-CoA + O2 = (2E)-tetradecenoyl-CoA + H2O2
    This reaction proceeds in the forward direction.
  • decanoyl-CoA + O2 = (2E)-decenoyl-CoA + H2O2
    This reaction proceeds in the forward direction.
  • dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2
    This reaction proceeds in the forward direction.
  • glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2
    This reaction proceeds in the forward direction.
  • hexanoyl-CoA + O2 = (2E)-hexenoyl-CoA + H2O2
    This reaction proceeds in the forward direction.

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Lipid metabolism; peroxisomal fatty acid beta-oxidation.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site140FAD (UniProtKB | ChEBI)
Binding site179FAD (UniProtKB | ChEBI)
Active site422Proton acceptor

GO annotations

AspectTerm
Cellular Componentmembrane
Cellular Componentperoxisome
Molecular FunctionFAD binding
Molecular Functionfatty acid binding
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionpalmitoyl-CoA oxidase activity
Biological Processfatty acid beta-oxidation using acyl-CoA oxidase
Biological Processlipid homeostasis
Biological Processvery long-chain fatty acid metabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Acyl-coenzyme A oxidase

Gene names

    • ORF names
      BRAFLDRAFT_274976

Organism names

Accessions

  • Primary accession
    C3YMS4

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane260-282Helical
Transmembrane332-354Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-134Acyl-coenzyme A oxidase N-terminal
Domain137-246Acyl-CoA oxidase/dehydrogenase middle
Domain315-437Acyl-CoA oxidase C-alpha1
Domain473-653Acyl-CoA oxidase C-terminal

Sequence similarities

Belongs to the acyl-CoA oxidase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    660
  • Mass (Da)
    73,952
  • Last updated
    2009-07-28 v1
  • MD5 Checksum
    C1A7C512E063986B19AC3BE577AB3C68
MNPDLKKERDGASFDPEKIVNFLYGGPDRVRRRREVVSLALDDPDFQHEDLNFMSREQQYETQLKKSILVVQKQKELGLVSPEDMGNYNYNGVFKSMSGPFGLHTSMFLPTLRGQATAEQKAKWLKMAENYAIIGTYAQTEMGHGTFLRGLETTSTYDPQTQEFVLNTPTPTGTKWWPGCLGKTSNYCVLMAQLYIHGKSYGPHPFMVQIRSLQDHKPLPGVTVGDIGPKFGYAGNDNGFLRFDNVRIPRDNMLMKYSRVMSFFCYLKTVLTPTTESVFLYLHMYSVETAPRPGRPSCAIDEASVGGPTWGVLQNRQPEPQVLDYVTQQYKLFPYLAAAYAFMLAARSMIFVYFRSMEKIGRGDITVLPELHALSSGLKSLSSWVMNAGIEECRMACGGHGYSHASGIPSIYMEHTPAATYEGENTVLMLQTARYLMKSYNQSLQGEKLAGSVAYLSGVQPVPAAGRTRNVLDLNVLIQAFQHRAARLVHEAALQLKKERQTGKDQPDAWNAAAVDLVKAAKAHSQYFVVKNFADRLTDPALDSAARAVLTRLCQLYALHDIVNSSGDFLEDGYLTGADIRQARRHINALMAKLRPDAVALVDAFDFPDGILNSILGRYDGNVYQHLLEWAKASPLNKTDVHESYYKYLKPFLEANRAKL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GG666531
EMBL· GenBank· DDBJ
EEN58415.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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