C3YM52 · C3YM52_BRAFL
- ProteinHistone deacetylase
- GeneLOC118431885
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids431 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- N6-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 95 | substrate | |||
Active site | 137 | Proton acceptor | |||
Binding site | 145 | substrate | |||
Binding site | 172 | a divalent metal cation (UniProtKB | ChEBI) | |||
Binding site | 174 | a divalent metal cation (UniProtKB | ChEBI) | |||
Binding site | 261 | a divalent metal cation (UniProtKB | ChEBI) | |||
Binding site | 300 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | histone deacetylase activity | |
Molecular Function | metal ion binding | |
Biological Process | epigenetic regulation of gene expression |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHistone deacetylase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Cephalochordata > Leptocardii > Amphioxiformes > Branchiostomatidae > Branchiostoma
Accessions
- Primary accessionC3YM52
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 24-315 | Histone deacetylase | |||
Region | 393-431 | Disordered | |||
Sequence similarities
Belongs to the histone deacetylase family. HD Type 1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length431
- Mass (Da)49,185
- Last updated2009-07-28 v1
- MD5 Checksum72EF37A3E9A41B376C4AD1BCC8417F2C
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A9J7NAM5 | A0A9J7NAM5_BRAFL | LOC118431885 | 406 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GG666529 EMBL· GenBank· DDBJ | EEN58646.1 EMBL· GenBank· DDBJ | Genomic DNA |