C3YDS7 · NNRE_BRAFL

Function

function

Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.

Catalytic activity

Cofactor

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: Binds 1 potassium ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site105-109(6S)-NADPHX (UniProtKB | ChEBI)
Binding site106K+ (UniProtKB | ChEBI)
Binding site170K+ (UniProtKB | ChEBI)
Binding site174-180(6S)-NADPHX (UniProtKB | ChEBI)
Binding site203(6S)-NADPHX (UniProtKB | ChEBI)
Binding site206K+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular FunctionNADHX epimerase activity
Molecular FunctionNADPHX epimerase activity
Molecular Functionnucleotide binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD(P)H-hydrate epimerase
  • EC number
  • Alternative names
    • NAD(P)HX epimerase

Gene names

    • ORF names
      BRAFLDRAFT_104103

Organism names

Accessions

  • Primary accession
    C3YDS7

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004163141-273NAD(P)H-hydrate epimerase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain52-260YjeF N-terminal

Sequence similarities

Belongs to the NnrE/AIBP family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    273
  • Mass (Da)
    30,292
  • Last updated
    2009-07-28 v1
  • Checksum
    12B4A1EBF1173EFF
MESWKGKYASGLRFSFRKRYSTEKGGTVDEDCEVISIGHKIGDISYVSQEEAQQIDQELFNEYAYSVDQLMELAGHSCAVALAKSYPLTSLKKDATVLVCCGPGNNGGDGLVCARHLKMFGYNPSVFYPKRTDKPLYKNLTIQCEQLDIPFLSHLPKPQLLSDGFSYIVDALFGFSFKGEVRPPFGDVLKTLKEVTVPICSIDVPSGWDVEGGNPDGLQPEFLISLTAPKKCAEKFAGRYHYLGGRFVPPGIIQKYELNLPTYPGTEPCIRLH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GG666504
EMBL· GenBank· DDBJ
EEN61546.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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