C3Y2L7 · C3Y2L7_BRAFL
- ProteinSialidase-1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids623 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage.
Catalytic activity
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | lysosomal lumen | |
Cellular Component | lysosomal membrane | |
Cellular Component | lysosome | |
Cellular Component | membrane | |
Molecular Function | exo-alpha-(2->3)-sialidase activity | |
Molecular Function | exo-alpha-(2->6)-sialidase activity | |
Molecular Function | exo-alpha-(2->8)-sialidase activity | |
Molecular Function | exo-alpha-sialidase activity | |
Biological Process | ganglioside catabolic process | |
Biological Process | oligosaccharide catabolic process |
Keywords
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSialidase-1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Cephalochordata > Leptocardii > Amphioxiformes > Branchiostomatidae > Branchiostoma
Accessions
- Primary accessionC3Y2L7
Subcellular Location
UniProt Annotation
GO Annotation
Lysosome membrane ; Peripheral membrane protein
Interaction
Subunit
Interacts with cathepsin A (protective protein), beta-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.
Protein-protein interaction databases
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length623
- Mass (Da)71,109
- Last updated2009-07-28 v1
- Checksum0D463FBDC30CCC0D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GG666482 EMBL· GenBank· DDBJ | EEN65279.1 EMBL· GenBank· DDBJ | Genomic DNA |