C3VM15 · C3VM15_9RHAB
- ProteinRNA-directed RNA polymerase L
- GeneL
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2095 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- GTP + H2O = GDP + H+ + phosphate
- a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine
- a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H+ + S-adenosyl-L-homocysteine
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | host cell cytoplasm | |
Cellular Component | membrane | |
Molecular Function | ATP binding | |
Molecular Function | hydrolase activity | |
Molecular Function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity | |
Molecular Function | RNA-dependent RNA polymerase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRNA-directed RNA polymerase L
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageViruses > Riboviria > Orthornavirae > Negarnaviricota > Haploviricotina > Monjiviricetes > Mononegavirales > Rhabdoviridae > Alpharhabdovirinae > Sprivivirus
Accessions
- Primary accessionC3VM15
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 825-843 | Helical | ||||
Sequence: YHYFANFCLLMIAMHNPAI | ||||||
Transmembrane | 864-886 | Helical | ||||
Sequence: AVTLYLDPSLGGVCGISLARFLI |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 587-773 | RdRp catalytic | ||||
Sequence: ICIANHIDYEKWNNHQRKESNGPVFRVMGQFLGYPRLFERTHEFFESSLIYYNGRPDLMDVRGDSLINTTEKLVCWEGQAGGLEGLRQKGWSVLNLLVINRESSIRNTIVKVLAQGDNQVICTQYKTKNYKNEEELKMLLSAMVDNNQTIMNSIVTGTGKLGLIINNDETMQSADYLNYGKMPVFRG | ||||||
Domain | 1625-1822 | Mononegavirus-type SAM-dependent 2'-O-MTase | ||||
Sequence: RVSQQATGAHYKLRSILKGLKIHYQDAIGCGDGSGGLSSCLLRENKHCKVIFNSLLELTGNTLRGSTPDPPSAINGIPQIRGRCVNLDNVWEYPSDLSHPDTWKYFKDLKEQFNLDIDLIVMDMEVQDVTISRKIEQNLRDSVASLLSKQGTVIYKTYMTILSENDQSVLETVGVLFEDVQLCQTQYSSSQTSEVYCV |
Sequence similarities
Belongs to the rhabdoviridae protein L family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,095
- Mass (Da)237,584
- Last updated2009-06-16 v1
- Checksum06B4A2EBB387BF3B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FJ872827 EMBL· GenBank· DDBJ | ACP28002.1 EMBL· GenBank· DDBJ | Viral cRNA |