C3U5A5 · C3U5A5_SAFV

Function

function

Affects membrane integrity and causes an increase in membrane permeability.
Forms a primer, VPg-pU, which is utilized by the polymerase for the initiation of RNA chains.
Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. Together they form an icosahedral capsid composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms.VP4 lies on the inner surface of the protein shell formed by VP1, VP2 and VP3. All the three latter proteins contain a beta-sheet structure called beta-barrel jelly roll. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes.
Serves as membrane anchor via its hydrophobic domain.
VP0 precursor is a component of immature procapsids.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentcytoplasmic vesicle membrane
Cellular Componenthost cell cytoplasmic vesicle membrane
Cellular Componenthost cell nucleolus
Cellular ComponentT=pseudo3 icosahedral viral capsid
Molecular FunctionATP binding
Molecular Functionchannel activity
Molecular Functioncysteine-type endopeptidase activity
Molecular FunctionRNA binding
Molecular FunctionRNA helicase activity
Molecular FunctionRNA-dependent RNA polymerase activity
Molecular Functionstructural molecule activity
Biological ProcessDNA-templated transcription
Biological Processmonoatomic ion transmembrane transport
Biological Processproteolysis
Biological Processsymbiont entry into host cell
Biological Processviral RNA genome replication
Biological Processvirion attachment to host cell

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Genome polyprotein

Gene names

    • Name
      gp1

Organism names

Accessions

  • Primary accession
    C3U5A5

Subcellular Location

Cytoplasmic vesicle membrane
; Peripheral membrane protein
Host cytoplasmic vesicle membrane
; Peripheral membrane protein
Host nucleus, host nucleolus
Membrane
; Peripheral membrane protein
Virion

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, coiled coil.

TypeIDPosition(s)Description
Domain1310-1475SF3 helicase
Coiled coil1553-1580
Domain1660-1853Peptidase C3
Domain2095-2213RdRp catalytic

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    2,318
  • Mass (Da)
    259,535
  • Last updated
    2009-06-16 v1
  • Checksum
    639293B2F85610EC
MCFTPSLWFKNCHSFSKPSGLGFLILLTGNMACKHGYPFLCPLCTAIDVSSDGSFALLFDNEWYPTDLLTVDLDDDVFYPLDCLMDWTDLPLIQDVLMEPQGNSNSSDKNNSQSSGNEGVIINNYYSNQYQNSIDLSANANGVGKENSKPQGQLMNILGSAADAFKNIAPLLMDQDTEEMTNLSDRVASDTAGNTATNTQSTVGRLFGYASRHRGKHPTSCADRATDKVLAAERYYTIKLATWDTTLKAFDHIRVPFPHILSGKEGGVFGATLRRHYLCKCGWRIQVQCNASQFHAGSLLIFMAPEFDTSPYESETEPDKNKVFTMDTTWQSGTKCLRGHSFESKTNQSLRPLSLNHQNTWQWTIYPHQILNLRTNTTCDIEVPYVNICPTSSWTQHANWTLVVAVLTPLQCPTGSAPDVEITASIQPVKPVFNGLRHSVLEPDSPFPGTIREHAGTFYSTTPDTTVPVYGKTISTPANYMCGEFTDLLSLCKIPTFIGNNLDSKWNPYFSSTNSVNENVSLVTYQVTLSSINLANTMLSSVARNFNQYRGSLNFLFVFTGSAMVKGKFLISYTPPGADKPKNRNQAMQATYAIWDLGLNSSYNFTVPFISPTHFRQTSYTTSTITSVDGWISVWQLTPLTYPANTPTHSDILTLVSGGDDFTLRMPVTPTKYVPHGVDNAEKGKVADDNASTDFVAEPVKLPENQTEVGFFYDRAVQACVLKSSQNFSDTFQLQSSDTLLNQTILTPLPNYKVDQSKEELVEQYRWLESAGTSTQPPYKTKQDWNFVMFSPFTYYKCDLEVTLTALNNNGQGALVRYSPCGAPADITTQTMSSTPSLADTRDPHMWFVGPGTTNQVSFVLPFTSPLSVLPAVWFNGYANFDNSSRYGVAPNADFGRLFVQGSGTFSVHFRYKKMRVFCPRPTVYFPWPSNPQRTKIHAENPVPILELQNPISIYRVDLFINFSDEIIQFTYKVHGRTVCQYEIPGFGLSRSGRLLVCMGEKPCQLPISTPKCFYHIVFTGSRNSFGVSIYKARYRPWKQPLHDELFDYGFSTFTDFFKAVRDYHASYYKQRLQHDIETNPGPVQSVFQLQGGVLTKSQAPMSGLQSMLLRAIGIEADCTEFTRAVNLITDLCNTWESAKTTLSSPEFWTKMVMRIVKMVAASVLYLHNPDLTTTVCLSLMAGIDILTNDSVFNWLSSKLSKFFHTPAPPIVPLLQQQSPIREANDNFNLAKNIEWAIKTIKRIVEWITSWFKQEETSPQAKLDKMLADFPEHCASILAMRNGRKAYTDCAGAFKYFEQLYNLAVQCKRIPLATLCEKFKNKHDHAVARPEPVVVVLRGNAGQGKSVTSQIIAQAVSKLSFGRQSVYSLPPDSDYLDGYENQYSVIMDDLGQNPDGEDFKVFCQMVSSTNFLPNMAHLEKKGTPFTSNFIIATTNLPKFRPVTVAHYPAVDRRITFDLTVEAGDECVTHNGMLDVEKAFEEIPGKPQLDCFNTDCRLLHKRGVRFVCNRTKNVYNLQQVVKMVKNTIDNKVENLKKMNTLVAQSPGNDMDYVLTCLRQTNAALQDQIDELQEAFNQAQERQNFLSDWLKVSAIVFASIASLSAVCKLVSRFKNLVCPAPVQIQLSEGEQAAYSGGKKGEKQTLQVLDVQGGGKIVAQAGNPVMDYEVNIAKNMVTPITFFYADKAQVTQSCLLIKGHLFVVNRHVAETDWCAFELKGTRHERDSVQMRSVNKSGMEVDLTFVKVVKGPLFKDNSKKFCSKDDDFPARNETVIGIMNTGVPFVFTGKFLIGNQPVNTTTGACFNHCIHYRATTHRGWGGSALICHVNGKKAVYAMHSAGGGGIAAATIITQEMIEAAEKALDCLTPQGAIVEIGIDTVVHVPRKTKLRRTVAHPCFQPKFEPAVLSRYDPRTTKDVDQVAFSKHTTNLEELPPVFTVVAKEYANRVFTTLGKENQILTPEQAILGLSGMDPMEKDTSPGLPYTQQGLKRAQLVNFEQGTMAQNLKEAHTKLTKGNYEDILYQSFLKDEIRPIEKIHEAKTRIVDVPPFHHCIWGRQLLGRFASKFQTNPGLDLGSAIGTDPDTDWTAFAFQLLQYKYVYDVDYSNFDASHSTAMFEILIENFFTVENGFDERIGDYLRSLAVSRHAFEERRVLVRGGLPSGCAATSMLNTIINNIVIRAALDLTYSNFEFDDIKVLSYGDDLLIATNYQINFNLVKQRLAPFNYKITPANKTVEFPETSNLYEVTFLKRKFVRHNSCLFKPQMDTENLKAMVSYCRPGTLKEKLNSIALLAVHSGKSVYDEIFDPFRRIGIIVPEHSTM

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue2318

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ463616
EMBL· GenBank· DDBJ
ACO92355.1
EMBL· GenBank· DDBJ
Genomic RNA

Similar Proteins

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