C2KZ86 · C2KZ86_9FIRM

  • Protein
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • Gene
    hppA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Requires K+ for maximal activity.

Features

Showing features for site.

TypeIDPosition(s)Description
Site441Determinant of potassium dependence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Molecular Functionpotassium ion binding
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • EC number
  • Alternative names
    • Membrane-bound sodium-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (Na(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      HMPREF6123_1805

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • F0268
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Oribacterium

Accessions

  • Primary accession
    C2KZ86

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane47-69Helical
Transmembrane76-97Helical
Transmembrane122-147Helical
Transmembrane154-176Helical
Transmembrane224-242Helical
Transmembrane249-271Helical
Transmembrane283-303Helical
Transmembrane310-329Helical
Transmembrane364-386Helical
Transmembrane446-464Helical
Transmembrane484-509Helical
Transmembrane546-566Helical
Transmembrane572-589Helical
Transmembrane637-659Helical

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    660
  • Mass (Da)
    67,824
  • Last updated
    2009-06-16 v1
  • Checksum
    DAF08584489E9B85
MNTMFMLVPVLGVLGLLFAFFQAQKIQKEDSGNERMKEIAHAIAEGAQAFLFAEYKILLFFVCSLFLCIGLGTRSWLSGAAFVFGALLSTLAGYFGMRSATAANVRTAEAARQSGMKKALSIAFSGGSVMGMSVAGFGIFGLGLFYYFTKDVGVLSGFSLGASSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGALVSAMTLGALAFQDKGIAFPLLLAGLSLLACILGSFSVVMIGGEDPSKVLKTASYSAAVAVIVFAFGLSNYFFGDFHAALAVTAGLIAGLCIGAITEYYTSSSYAPVKEIAKQSETGSATNIISGMAIGMRSTAIPILLISVAIFVSFSLLGLYGIALSAVGMLSTTAITVAVDAYGPIADNAGGIAEMAGLEEGVRKITDQLDAVGNTTAAMGKGFAIGSAALTALALFASYAEAVQLKSINVLDSRVCIGLFIGAMLPFLFSAFTMSSVSKAAFAMISEVRRQFKEKPGIMAGTDKPDYKTCVSISTRAALREMIVPGVLAVIAPLAIGLLLGAEALGGLLAGSLVSGVMMAIFMSNSGGAWDNAKKYIEEGHNGGKGSETHKAAVVGDTVGDPFKDTSGPSINILIKLMTVIALVFAPLIMTLGGIL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ACKX01000181
EMBL· GenBank· DDBJ
EEJ50938.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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