C2KZ86 · C2KZ86_9FIRM
- ProteinPutative K(+)-stimulated pyrophosphate-energized sodium pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids660 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.
Catalytic activity
- Na+(in) + diphosphate + H2O = Na+(out) + 2 phosphate + H+Na+ (in)CHEBI:29101
+ CHEBI:33019 + CHEBI:15377 = Na+ (out)CHEBI:29101+ 2 CHEBI:43474 + CHEBI:15378
Cofactor
Activity regulation
Requires K+ for maximal activity.
Features
Showing features for site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 441 | Determinant of potassium dependence | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | potassium ion binding | |
Biological Process | sodium ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative K(+)-stimulated pyrophosphate-energized sodium pump
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Oribacterium
Accessions
- Primary accessionC2KZ86
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endomembrane system ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 47-69 | Helical | |||
Transmembrane | 76-97 | Helical | |||
Transmembrane | 122-147 | Helical | |||
Transmembrane | 154-176 | Helical | |||
Transmembrane | 224-242 | Helical | |||
Transmembrane | 249-271 | Helical | |||
Transmembrane | 283-303 | Helical | |||
Transmembrane | 310-329 | Helical | |||
Transmembrane | 364-386 | Helical | |||
Transmembrane | 446-464 | Helical | |||
Transmembrane | 484-509 | Helical | |||
Transmembrane | 546-566 | Helical | |||
Transmembrane | 572-589 | Helical | |||
Transmembrane | 637-659 | Helical | |||
Keywords
- Cellular component
Interaction
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length660
- Mass (Da)67,824
- Last updated2009-06-16 v1
- ChecksumDAF08584489E9B85
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ACKX01000181 EMBL· GenBank· DDBJ | EEJ50938.1 EMBL· GenBank· DDBJ | Genomic DNA |