C2CF82 · C2CF82_9FIRM

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

Type
IDPosition(s)Description
Site27Important for substrate specificity
Active site92Proton acceptor
Site93Important for substrate specificity
Site178Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctiondTTP diphosphatase activity
Molecular FunctionUTP diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • ORF names
      HMPREF0077_0142

Organism names

Accessions

  • Primary accession
    C2CF82

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    212
  • Mass (Da)
    24,563
  • Last updated
    2009-06-16 v1
  • Checksum
    D6574143C568FC84
MKYNYDYEKVGKIEKFDKVILMSKSPRRRDLLNFLKPDVCSIEINEREIQKKFMDLYADDSFLLMAGKTCCEIAKAKSHVFLKEKNLYISSDTMVLMGDKIYGKPANLKEARLMFMSYFGKSHYVISAVCLREKSYLDVFFSLAEVRFCDYYKELDPLIEDYLIEENVGDKAGSYGIQDLDPRFISYINGDINTIIGLPVSELSRRISGGYK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ACGC01000009
EMBL· GenBank· DDBJ
EEI83701.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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