C1D5G4 · ATPA_LARHH
- ProteinATP synthase subunit alpha
- GeneatpA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids514 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
Catalytic activity
- ATP + H2O + 4 H+(in) = ADP + phosphate + 5 H+(out)
CHEBI:30616 + CHEBI:15377 + 4 H+ (in)CHEBI:15378= CHEBI:456216 + CHEBI:43474 + 5 H+ (out)CHEBI:15378
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 169-176 | ATP (UniProtKB | ChEBI) | |||
Site | 373 | Required for activity | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Cellular Component | proton-transporting ATP synthase complex, catalytic core F(1) | |
Molecular Function | ADP binding | |
Molecular Function | ATP binding | |
Molecular Function | proton-transporting ATP synthase activity, rotational mechanism | |
Molecular Function | proton-transporting ATPase activity, rotational mechanism |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP synthase subunit alpha
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Aquaspirillaceae > Laribacter
Accessions
- Primary accessionC1D5G4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000166543 | 1-514 | ATP synthase subunit alpha | ||
Interaction
Subunit
F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length514
- Mass (Da)55,096
- Last updated2009-05-26 v1
- ChecksumE52B2AA6E46AA7E5
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001154 EMBL· GenBank· DDBJ | ACO75981.1 EMBL· GenBank· DDBJ | Genomic DNA |