C1BA77 · COAX_RHOOB
- ProteinType III pantothenate kinase
- GenecoaX
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids271 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
Catalytic activity
- (R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H+
Cofactor
K+ (UniProtKB | Rhea| CHEBI:29103 )
Note: A monovalent cation. Ammonium or potassium.
Pathway
Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 6-13 | ATP (UniProtKB | ChEBI) | |||
Binding site | 109-112 | substrate | |||
Active site | 111 | Proton acceptor | |||
Binding site | 131 | K+ (UniProtKB | ChEBI) | |||
Binding site | 134 | ATP (UniProtKB | ChEBI) | |||
Binding site | 186 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | pantothenate kinase activity | |
Biological Process | coenzyme A biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameType III pantothenate kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Nocardiaceae > Rhodococcus
Accessions
- Primary accessionC1BA77
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000165205 | 1-271 | Type III pantothenate kinase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length271
- Mass (Da)29,293
- Last updated2009-05-26 v1
- Checksum680459752E6D0A8E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP011115 EMBL· GenBank· DDBJ | BAH52580.1 EMBL· GenBank· DDBJ | Genomic DNA |