C1BA77 · COAX_RHOOB

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Catalytic activity

Cofactor

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

127120406080100120140160180200220240260
Type
IDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site109-112substrate
Active site111Proton acceptor
Binding site131K+ (UniProtKB | ChEBI)
Binding site134ATP (UniProtKB | ChEBI)
Binding site186substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • Ordered locus names
      ROP_43330

Organism names

Accessions

  • Primary accession
    C1BA77

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001652051-271Type III pantothenate kinase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    271
  • Mass (Da)
    29,293
  • Last updated
    2009-05-26 v1
  • Checksum
    680459752E6D0A8E
MLLTVDVRNTNIVLGLFTGTGEHSKLVQDWRMRTDARMTADELALIFRGLLGAHTDQITGVSALSTVPSVLREIRVMLTRYWGHVPHVLVEPGVRTGVPLLVDNPKEVGADRIVNSLAAHHLYDAPCIVVDFGTSTCVDVVSAKGEFLGGAIAPGLEISSDALASQSAALRKVELVRPRSVVGKNTVECMQSGAVFGFAGLVDGLVRRVRRELPAFSGSDVVVIATGDRAPLIMPETETVDEHEPDLTLEGLRLVYERNQARRGARRSPLD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP011115
EMBL· GenBank· DDBJ
BAH52580.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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