C1A9T6 · ACKA_GEMAT
- ProteinAcetate kinase
- GeneackA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids412 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
Catalytic activity
- acetate + ATP = acetyl phosphate + ADP
Cofactor
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Mg2+. Can also accept Mn2+.
Pathway
Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 7 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 14 | ATP (UniProtKB | ChEBI) | |||
Binding site | 98 | substrate | |||
Active site | 156 | Proton donor/acceptor | |||
Site | 188 | Transition state stabilizer | |||
Binding site | 216-220 | ATP (UniProtKB | ChEBI) | |||
Site | 249 | Transition state stabilizer | |||
Binding site | 291-293 | ATP (UniProtKB | ChEBI) | |||
Binding site | 340-344 | ATP (UniProtKB | ChEBI) | |||
Binding site | 395 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | acetate kinase activity | |
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Biological Process | acetate metabolic process | |
Biological Process | acetyl-CoA biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetate kinase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Gemmatimonadota > Gemmatimonadia > Gemmatimonadales > Gemmatimonadaceae > Gemmatimonas
Accessions
- Primary accessionC1A9T6
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000201905 | 1-412 | Acetate kinase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length412
- Mass (Da)44,401
- Last updated2009-05-26 v1
- Checksum20D38FFA0F07A547
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP009153 EMBL· GenBank· DDBJ | BAH39263.1 EMBL· GenBank· DDBJ | Genomic DNA |