C0ZGQ4 · C0ZGQ4_BREBN
- ProteinPutative polyketide synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids3732 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Pathway
Antibiotic biosynthesis; bacillaene biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 17 | Proton acceptor; for dehydratase activity | ||||
Sequence: H | ||||||
Active site | 190 | Proton donor; for dehydratase activity | ||||
Sequence: D | ||||||
Active site | 1151 | Proton acceptor; for dehydratase activity | ||||
Sequence: H | ||||||
Active site | 1324 | Proton donor; for dehydratase activity | ||||
Sequence: D |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Molecular Function | 3-oxoacyl-[acyl-carrier-protein] synthase activity | |
Molecular Function | phosphopantetheine binding | |
Biological Process | fatty acid biosynthetic process |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Paenibacillaceae > Brevibacillus
Accessions
- Primary accessionC0ZGQ4
Proteomes
PTM/Processing
Keywords
- PTM
Interaction
Protein-protein interaction databases
Family & Domains
Features
Showing features for region, domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-114 | N-terminal hotdog fold | ||||
Sequence: MHDQFLITINHPILKNHKVHGQELLPGLAHIDLLYQMFRENGHGYRELELRNLTIYHPIMVGQDYDVMLSIQCTQVKAGQWQIRMEGQTQRNGILDSEKKLYVTAEMHHHASAP | ||||||
Domain | 1-276 | PKS/mFAS DH | ||||
Sequence: MHDQFLITINHPILKNHKVHGQELLPGLAHIDLLYQMFRENGHGYRELELRNLTIYHPIMVGQDYDVMLSIQCTQVKAGQWQIRMEGQTQRNGILDSEKKLYVTAEMHHHASAPFDETLDLPLLEQAANKKINLHDVYEQCRRQELVHIGFMKAEGTIYETDSAAVMDISLGKHALPSAEGFMFHPTLIDGAAIGSMVLFTSIVQEEQRLFLPLFYESFRATALLQQHCFVSVQTSSIQRKNELMYMTMEFFDRSGKKIAHLQNFAGKLVRDPGLI | ||||||
Region | 129-276 | C-terminal hotdog fold | ||||
Sequence: NKKINLHDVYEQCRRQELVHIGFMKAEGTIYETDSAAVMDISLGKHALPSAEGFMFHPTLIDGAAIGSMVLFTSIVQEEQRLFLPLFYESFRATALLQQHCFVSVQTSSIQRKNELMYMTMEFFDRSGKKIAHLQNFAGKLVRDPGLI | ||||||
Domain | 290-364 | Carrier | ||||
Sequence: SKAQAFLQQLLAERLQVPAALIDTQIGYYEMGLNSPGLLEVVKAVEAKVGVPLSPTLLFEYTNIAELAAYLTENH | ||||||
Domain | 403-840 | Ketosynthase family 3 (KS3) | ||||
Sequence: DEEIAIIGMAGRYPEARNLQEFWMNLKEGKDCIKEVPKSRWDWQQFGELKSPSGKQISKWGGFIEDPDCFDSSFFRISPREAETMDPQERLFLETCWEAMEDAGYTPKTIVPPRGSSNRRQVGVFVGVMHKDYSLIGAEAMSRGEMFPLSLNYAPIANRVSYFCNFHGPSMAIDTVCSSSLTAVHLALESIKRGECEVALAGGVNLSLHPGKYLSYGLMDMHASDGYCHTFGKDGDGYVSGEGVGTVVLKPLRKAIEDGDHIYAVVKGSSVNHVGSVSGPSVPSPVAQAEVITACLEKSGVDARTIRYVEAHGTGTSLGDPIEIQGLVKAFRQYTEDQQFCSIGSVKSNIGHAESAAGISGLQKAVLQLHHKTLVASLHAKEVNPFIDFAQSPFYVQQRTEEWKSVIVENGQEVSVPRRAGVSSFGASGSNAHIILEE | ||||||
Domain | 891-968 | Carrier | ||||
Sequence: HLQEMLEKKLRKILSSIIHVGENSIESEQEWHEYGVDLVQLTQLKQKLQEELPIQLDIKEFDQSSSIASVIASLMDNH | ||||||
Region | 1122-1248 | N-terminal hotdog fold | ||||
Sequence: HPLLQRNTSDFSVTRFSSTFTGQEFFLTDHVVKKQRILPGVAYLEMARAAAEQATASLTEEPAKIALKNVVWTRPIVVGDQPVQIHIGLVPEENGEITYEIYSNLEAMDAEPVIHSQGSVMLHSVAE | ||||||
Domain | 1122-1418 | PKS/mFAS DH | ||||
Sequence: HPLLQRNTSDFSVTRFSSTFTGQEFFLTDHVVKKQRILPGVAYLEMARAAAEQATASLTEEPAKIALKNVVWTRPIVVGDQPVQIHIGLVPEENGEITYEIYSNLEAMDAEPVIHSQGSVMLHSVAEKHALNLSSLQTECSLRAFSSEQCYSIFHAIGMEYGSAHQGIDTLYVGEGQVLAKLSLPASVSETENSFVLHPSLMDSALQASIGLMLVEEETSTADGHSSRKPSLPFAMEEVDIHNKCTASMWAYVRYSANSSADDKVQRLDIDLCDDQGNVCVRIKGYSMRVLEDGKQA | ||||||
Region | 1262-1418 | C-terminal hotdog fold | ||||
Sequence: SLRAFSSEQCYSIFHAIGMEYGSAHQGIDTLYVGEGQVLAKLSLPASVSETENSFVLHPSLMDSALQASIGLMLVEEETSTADGHSSRKPSLPFAMEEVDIHNKCTASMWAYVRYSANSSADDKVQRLDIDLCDDQGNVCVRIKGYSMRVLEDGKQA | ||||||
Domain | 2105-2178 | Carrier | ||||
Sequence: EKSTAYFKQLVGETLKIPFDQIDSSAALEEYGIDSIMIVQMTNVLRKKLHQISTTLFFEYQTIDALVEHFMTTQ | ||||||
Domain | 2240-2659 | Ketosynthase family 3 (KS3) | ||||
Sequence: RQDVAIIGLSGRYPQAGDVREFWTRLKEGKNCITEVPKDRWNWQEYFSEEKGKRGYMYTKWGGFIEDMDKFDPLFFQISPNEAEQMDPQERLFLQTAYASMEDAGYTPATLGESRKIGVFVGVMNGNYPAGTSYWSIANRISYLFNFQGPSLAVDTACSSSLTAIHLALESLYSGTSECAIAGGVNLIVDPFHYIRLSGATMLSAGDRCKSFGDQADGFVDGEGVGAIVLKPLQKAIADGDHIYGVIKGSMLNAGGKTNGYTVPNPIAQSQVIHEALQRAGVDARAVSYIEAHGTGTALGDPIEIAGLTRAFGQYTKDKQFCAIGSAKSNIGHTESAAGIAGLTKILLQMKYGQIAPSLHAEVKNPNIDFRDTPFAVQQKLTEWQRPVIEINGVTKEYPRIAGLSSFGAGGANVHIVIEE | ||||||
Coiled coil | 2683-2741 | |||||
Sequence: AKNEERLFAQVNQLLKAVKEESFTDADLADIAYTLQVGREALEERLAVIVRSVDELAEK | ||||||
Region | 2851-2977 | N-terminal hotdog fold | ||||
Sequence: HPLLHKNTSDLYELRYSSSFTGQELFMADHLGNGQRFFPLIAYLEMARAAVKQAAGERAGTLSGIRMSHVATDDPLLVGDDLVQVHVGIYPEDTGELAYKIYSESNEDDTRSVVHSHGMVEFTSFVE | ||||||
Domain | 2851-3143 | PKS/mFAS DH | ||||
Sequence: HPLLHKNTSDLYELRYSSSFTGQELFMADHLGNGQRFFPLIAYLEMARAAVKQAAGERAGTLSGIRMSHVATDDPLLVGDDLVQVHVGIYPEDTGELAYKIYSESNEDDTRSVVHSHGMVEFTSFVEVPTLDLPALQAESSEILTARQCYELLKERGMADHSEFQGIDQVYRAPGHVLVKLSLPSITMETAEQLVFHPSLLESLLPSTRYLITEATSPDSIRSIQLDGTFTLEELEIYENHPAVKYALIRFSDNVQAENETATLDIELCDEAGRIGIRMRGFSMGSEKRGATV | ||||||
Region | 2991-3143 | C-terminal hotdog fold | ||||
Sequence: SEILTARQCYELLKERGMADHSEFQGIDQVYRAPGHVLVKLSLPSITMETAEQLVFHPSLLESLLPSTRYLITEATSPDSIRSIQLDGTFTLEELEIYENHPAVKYALIRFSDNVQAENETATLDIELCDEAGRIGIRMRGFSMGSEKRGATV | ||||||
Domain | 3642-3716 | Carrier | ||||
Sequence: DDVQATIIQLASLILKVESEEIDTDIELKEYGFDPVKLTEFSAKINQKYKLELTPAVMLDYPTLKHITEFLVNTT |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length3,732
- Mass (Da)415,126
- Last updated2009-05-26 v1
- Checksum9CCD6313AF23F87B
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP008955 EMBL· GenBank· DDBJ | BAH44963.1 EMBL· GenBank· DDBJ | Genomic DNA |