C0XJ92 · C0XJ92_LENH9

Function

function

Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
    EC:2.7.13.3 (UniProtKB | ENZYME | Rhea)

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentmembrane
Molecular Function4 iron, 4 sulfur cluster binding
Molecular FunctionATP binding
Molecular Functioniron ion binding
Molecular Functionphosphorelay sensor kinase activity
Molecular Functionprotein dimerization activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Sensor histidine kinase
  • EC number

Gene names

    • ORF names
      HMPREF0519_1303

Organism names

Accessions

  • Primary accession
    C0XJ92

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Cytoplasm

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue150Phosphohistidine; by autocatalysis

Post-translational modification

Autophosphorylated.

Keywords

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain152-341Histidine kinase

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    342
  • Mass (Da)
    38,812
  • Last updated
    2009-05-26 v1
  • Checksum
    31B55C075F876963
MLETQNWIKRYFDDETDAILIFANNDLIVCNRIANDLQKIVKIDPQYLLEVANTAVKQRFSQTDSCFSCAIKNHMQEISIPITLAQESAHPLRYFLVYRLIDKDDHVFSLTLKNRGVIKRMDQLAQQRQLNQYVNRAHEEERKRILQDLHDSIAQGVYSAIMGVRRLSEDVLTHDQVTELTREIEHQLNDTLTEVKGMALDIRPSVLDNFGLLPALRVLAKRLSENSGVNISVVGNAKTDNLSTDVQSVLYRIGQESINNALKHAQASEINILLVAHEHYIMLEIIDDGIGFDVPKHHRFNGRSLGLMNMNERIKALNGTFEIKSQPGSGTTVTAKFPVVLS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ACGP01000125
EMBL· GenBank· DDBJ
EEI24566.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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