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C0VZR7 · C0VZR7_9ACTO

  • Protein
    N5-carboxyaminoimidazole ribonucleotide mutase
  • Gene
    purE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site10substrate
Binding site13substrate
Binding site40substrate

GO annotations

AspectTerm
Molecular Function5-(carboxyamino)imidazole ribonucleotide mutase activity
Molecular Functionlyase activity
Biological Process'de novo' IMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    N5-carboxyaminoimidazole ribonucleotide mutase
  • EC number
  • Short names
    N5-CAIR mutase
  • Alternative names
    • 5-(carboxyamino)imidazole ribonucleotide mutase

Gene names

    • Name
      purE
    • ORF names
      HMPREF0044_0795

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 15436
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Actinomycetales > Actinomycetaceae > Gleimia

Accessions

  • Primary accession
    C0VZR7

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-155PurE

Sequence similarities

Belongs to the AIR carboxylase family. Class I subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    167
  • Mass (Da)
    17,551
  • Last updated
    2009-05-26 v1
  • MD5 Checksum
    A7C199857C54C1E9EAD1C47A1A2ACDA2
MAKVGIVMGSDSDWRVMHEVGEALDEFGIEYVVGVVSAHRMPEEMIAYGKTAHEKGIGVIVAGAGGAAHLPGMLAAVTPLPVIGVPVPLKYLDGMDSLLSIVQMPAGVPVATVSIGGARNAGLLAARILGASEGVEAERIRKQMLEFQADLKRIAQEKGERLKENLN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ACFG01000030
EMBL· GenBank· DDBJ
EEH63776.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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