C0RIJ9 · COBS_BRUMB
- ProteinAdenosylcobinamide-GDP ribazoletransferase
- GenecobS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids260 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
Catalytic activity
- adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H+
Cofactor
Pathway
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | adenosylcobinamide-GDP ribazoletransferase activity | |
Molecular Function | cobalamin 5'-phosphate synthase activity | |
Biological Process | cobalamin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAdenosylcobinamide-GDP ribazoletransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Brucellaceae > Brucella/Ochrobactrum group > Brucella
Accessions
- Primary accessionC0RIJ9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 42-62 | Helical | ||||
Sequence: PLAGGILGLLAGVALLIANAI | ||||||
Transmembrane | 64-84 | Helical | ||||
Sequence: LPPLAAALIAIGALAAMTGAL | ||||||
Transmembrane | 117-137 | Helical | ||||
Sequence: FAALTLVIWTGVKASLLMAII | ||||||
Transmembrane | 144-164 | Helical | ||||
Sequence: YALLALIGTEAASRAGMLAFW | ||||||
Transmembrane | 192-212 | Helical | ||||
Sequence: GLGLALLAIGFLPSGGMVALI | ||||||
Transmembrane | 214-234 | Helical | ||||
Sequence: ALVLMTVVLFGFARLCMAKIG | ||||||
Transmembrane | 240-260 | Helical | ||||
Sequence: TLGAAQQIGSLAALIGLVMAL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000148017 | 1-260 | Adenosylcobinamide-GDP ribazoletransferase | |||
Sequence: MQRNGLIGDTIRSLGFLSRLPLPQGWFDNTDDSLPRNARAFPLAGGILGLLAGVALLIANAISLPPLAAALIAIGALAAMTGALHEDGLGDTADGFFGASTPDRRLDIMKDSRIGTFAALTLVIWTGVKASLLMAIIARAGAGYALLALIGTEAASRAGMLAFWHALPSARPGGLADSMGQPQWETVVCGCGLGLALLAIGFLPSGGMVALINALVLMTVVLFGFARLCMAKIGGRTGDTLGAAQQIGSLAALIGLVMAL |
Structure
Sequence
- Sequence statusComplete
- Length260
- Mass (Da)26,432
- Last updated2009-05-05 v1
- ChecksumE3E7A67924301DF0
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001488 EMBL· GenBank· DDBJ | ACO00657.1 EMBL· GenBank· DDBJ | Genomic DNA |