C0QYU7 · ARGC_BRAHW
- ProteinN-acetyl-gamma-glutamyl-phosphate reductase
- GeneargC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids352 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
Catalytic activity
- N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = H+ + N-acetyl-L-glutamyl 5-phosphate + NADPH
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 3/4.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 155 | |||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | N-acetyl-gamma-glutamyl-phosphate reductase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP+ binding | |
Biological Process | arginine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameN-acetyl-gamma-glutamyl-phosphate reductase
- EC number
- Short namesAGPR
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Spirochaetota > Spirochaetia > Brachyspirales > Brachyspiraceae > Brachyspira
Accessions
- Primary accessionC0QYU7
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000123234 | 1-352 | N-acetyl-gamma-glutamyl-phosphate reductase | |||
Sequence: MIKVSVIGATGYAGAELIRLLLSHSKVELKNLSSKSFVGKNINEIYPNLNKNLDKLLLDENEIFEDTDVVFASLPAGLSDDIANKCFEKNILFIDLGADFRLDNEEDYKNWYGNEYKYKNLHKEAIYSIPEIIKYDNVYNKKELKNAKIIGNPGCYPTSIGLALAPALVNKFIIKDDIIIDSKSGATGAGRELKLNTHYTECNEAFAPYKIAEHRHTPEIEQTLSNIYGEDIKVTFVPHLLPLNRGIVSTIYAKLENKNIKLKDIHNTYKNFYKDSAFVRVLNIGEIANLKYVKYSNYCDISLHMDDRTNKLIIVSTIDNMVKGAAGQAIQNMNIALGLKEDEGLNFIPPAF |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length352
- Mass (Da)39,651
- Last updated2009-05-05 v1
- Checksum8E55AFC386FF49C0
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001357 EMBL· GenBank· DDBJ | ACN83035.1 EMBL· GenBank· DDBJ | Genomic DNA |