C0LJI8 · C0LJI8_9EURY
- ProteinDNA ligase
- Genelig
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids559 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
Catalytic activity
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 247 | ATP (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Active site | 249 | N6-AMP-lysine intermediate | ||||
Sequence: K | ||||||
Binding site | 254 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 269 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 299 | ATP (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 339 | ATP (UniProtKB | ChEBI) | ||||
Sequence: F | ||||||
Binding site | 414 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 420 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | DNA binding | |
Molecular Function | DNA ligase (ATP) activity | |
Molecular Function | metal ion binding | |
Biological Process | cell division | |
Biological Process | DNA biosynthetic process | |
Biological Process | DNA recombination | |
Biological Process | DNA repair | |
Biological Process | DNA replication |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Thermococci > Thermococcales > Thermococcaceae > Thermococcus
Accessions
- Primary accessionC0LJI8
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 327-455 | ATP-dependent DNA ligase family profile | ||||
Sequence: EMIEKIPLELNLFDILYVDGESLIDTEFVERRKRLEESVEESEKIKIAEQLVTKKVEEAEAFYKRALELGHEGLMAKRLDSVYEPGNRGKKWLKIKPTMENLDLVIIGAEWGEGRRAHLLGSFLVAAYD |
Sequence similarities
Belongs to the ATP-dependent DNA ligase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length559
- Mass (Da)63,521
- Last updated2009-05-05 v1
- ChecksumF6B9EB2CB724278A
Keywords
- Technical term