C0LGF4 · FEI1_ARATH

Function

function

Involved in the signaling pathway that regulates cell wall function, including cellulose biosynthesis, likely via an 1-aminocyclopropane-1-carboxylic acid (ACC)-mediated signal (a precursor of ethylene).

Miscellaneous

'Fei' means fat in Chinese.

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site312-320ATP (UniProtKB | ChEBI)
Binding site334ATP (UniProtKB | ChEBI)
Active site429Proton acceptor

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functionprotein serine kinase activity
Molecular Functionprotein serine/threonine kinase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    LRR receptor-like serine/threonine-protein kinase FEI 1
  • EC number

Gene names

    • Name
      FEI1
    • ORF names
      T8E3.2
    • Ordered locus names
      At1g31420

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    C0LGF4
  • Secondary accessions
    • Q9C867

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Cell membrane
; Single-pass type I membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain30-238Extracellular
Transmembrane239-259Helical
Topological domain260-591Cytoplasmic

Keywords

Phenotypes & Variants

Disruption phenotype

No visible phenotype. Fei1 and fei2 double mutants exhibit disrupted anisotropic expansion (e.g. during hypocotyl elongation), impaired synthesis of cell wall polymers, and abnormal cellulose biosynthesis.

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis334Loss of kinase activity, normal interaction with ACC synthases.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 50 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for signal, chain, glycosylation, modified residue.

TypeIDPosition(s)Description
Signal1-29
ChainPRO_000038751130-591LRR receptor-like serine/threonine-protein kinase FEI 1
Glycosylation80N-linked (GlcNAc...) asparagine
Glycosylation120N-linked (GlcNAc...) asparagine
Glycosylation176N-linked (GlcNAc...) asparagine
Modified residue386Phosphoserine
Modified residue462Phosphothreonine
Modified residue463Phosphothreonine
Modified residue468Phosphothreonine
Modified residue476Phosphotyrosine

Post-translational modification

Autophosphorylated.

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in the root meristem and elongation zone, and in hypocotyls of etiolated seedlings.

Gene expression databases

Interaction

Subunit

Interacts with the ACC synthases ACS5 and ACS9 but not ACS2, via the kinase domain.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY C0LGF4At1g17230 Q9SHI22EBI-16896366, EBI-20651261
BINARY C0LGF4At2g02780 C0LGJ92EBI-16896366, EBI-20651541

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for repeat, domain.

TypeIDPosition(s)Description
Repeat73-97LRR 1
Repeat98-121LRR 2
Repeat123-145LRR 3
Repeat146-169LRR 4
Repeat171-194LRR 5
Domain306-578Protein kinase

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.

This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.

C0LGF4-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    591
  • Mass (Da)
    64,916
  • Last updated
    2009-05-05 v1
  • Checksum
    EA57944B55157D91
MMGICEMKSCCSWLLLISLLCSLSNESQAISPDGEALLSFRNAVTRSDSFIHQWRPEDPDPCNWNGVTCDAKTKRVITLNLTYHKIMGPLPPDIGKLDHLRLLMLHNNALYGAIPTALGNCTALEEIHLQSNYFTGPIPAEMGDLPGLQKLDMSSNTLSGPIPASLGQLKKLSNFNVSNNFLVGQIPSDGVLSGFSKNSFIGNLNLCGKHVDVVCQDDSGNPSSHSQSGQNQKKNSGKLLISASATVGALLLVALMCFWGCFLYKKLGKVEIKSLAKDVGGGASIVMFHGDLPYSSKDIIKKLEMLNEEHIIGCGGFGTVYKLAMDDGKVFALKRILKLNEGFDRFFERELEILGSIKHRYLVNLRGYCNSPTSKLLLYDYLPGGSLDEALHERGEQLDWDSRVNIIIGAAKGLSYLHHDCSPRIIHRDIKSSNILLDGNLEARVSDFGLAKLLEDEESHITTIVAGTFGYLAPEYMQSGRATEKTDVYSFGVLVLEVLSGKRPTDASFIEKGLNVVGWLKFLISEKRPRDIVDPNCEGMQMESLDALLSIATQCVSPSPEERPTMHRVVQLLESEVMTPCPSEFYDSSSD

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
F4I9D5F4I9D5_ARATHFEI1592

Sequence caution

The sequence AAG51266.1 differs from that shown. Reason: Erroneous initiation

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC027135
EMBL· GenBank· DDBJ
AAG51266.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation
CP002684
EMBL· GenBank· DDBJ
AEE31354.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ708643
EMBL· GenBank· DDBJ
ACN59239.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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