NLRP1 promoted myofibroblast differentiation and excessive ECM production in TGF-beta1-induced neonatal cardiac fibroblasts through directly targeting TGF-beta1/Smad signaling pathways.
toxin-mediated lethality in rats as well as macrophage sensitivity in anthrax animal model are controlled by a single locus on chromosome 10 that is likely to be the inflammasome NLR sensor Nlrp1
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