C0HK41 · CYMC7_MELCT
- ProteinCyclotide mech-7
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Probably participates in a plant defense mechanism (Potential). Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE) (By similarity).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Biological Process | defense response |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameCyclotide mech-7
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Malpighiales > Violaceae > Melicytus
Accessions
- Primary accessionC0HK41
PTM/Processing
Features
Showing features for peptide, cross-link, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Peptide | PRO_0000437520 | 1-29 | Cyclotide mech-7 | |||
Sequence: GIPICGETCTIGTCNTPGCTCSWPVCTRD | ||||||
Cross-link | 1↔29 | Cyclopeptide (Gly-Asp) | ||||
Sequence: GIPICGETCTIGTCNTPGCTCSWPVCTRD | ||||||
Disulfide bond | 5↔19 | |||||
Sequence: CGETCTIGTCNTPGC | ||||||
Disulfide bond | 9↔21 | |||||
Sequence: CTIGTCNTPGCTC | ||||||
Disulfide bond | 14↔26 | |||||
Sequence: CNTPGCTCSWPVC |
Post-translational modification
This is a cyclic peptide.
Contains 3 disulfide bonds.
Keywords
- PTM
Structure
Family & Domains
Domain
The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.
Sequence similarities
Belongs to the cyclotide family. Moebius subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length29
- Mass (Da)2,989
- Last updated2016-10-05 v1
- Checksum3CD090077937FA18
Features
Showing features for sequence uncertainty.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence uncertainty | 2 | I or L | ||||
Sequence: I | ||||||
Sequence uncertainty | 4 | I or L | ||||
Sequence: I | ||||||
Sequence uncertainty | 11 | I or L | ||||
Sequence: I |
Mass Spectrometry
Keywords
- Technical term