C0ERJ0 · C0ERJ0_NEIFL

Function

function

Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: Binds 1 potassium ion per subunit.

Features

Showing features for binding site.

133550100150200250300
TypeIDPosition(s)Description
Binding site24(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)
Binding site82(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)
Binding site121(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)
Binding site227K+ (UniProtKB | ChEBI)
Binding site227-232GTP (UniProtKB | ChEBI)
Binding site231Mg2+ (UniProtKB | ChEBI)
Binding site246K+ (UniProtKB | ChEBI)
Binding site246-252GTP (UniProtKB | ChEBI)
Binding site248K+ (UniProtKB | ChEBI)
Binding site251K+ (UniProtKB | ChEBI)
Binding site252Mg2+ (UniProtKB | ChEBI)
Binding site271-274GTP (UniProtKB | ChEBI)
Binding site329(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionmetal ion binding
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA modification GTPase MnmE
  • EC number

Gene names

    • Name
      mnmE
    • Synonyms
      trmE
    • ORF names
      NEIFLAOT_02592

Organism names

Accessions

  • Primary accession
    C0ERJ0

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain217-335TrmE-type G

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    335
  • Mass (Da)
    35,334
  • Last updated
    2009-05-05 v1
  • Checksum
    308413A55F8CBD84
MSATQPTIAAIATAPGRGGVGVIRLSGKNLLPLAQTLSGGKTPKPRTALYTDFLGGDGQPIDNGILLYFAAPASFTGEDVIELQGHGGPVVMDMLLSRCLELGARMAEPGEFTKRAFLNNKLDLAQAESVADLIDASSKSAARMALRSLKGAFSQHIHELVDDLITLRMLVEATLDFPEEDIDFLEAADARGKLQALQGRLKTVLASAEQGAILREGMNVVLVGAPNVGKSSLLNALAGDDIAIVTDIAGTTRDTVREQITLDGVPVHIIDTAGLRETDDVVEQIGIERSRKAVSEADVALILIDPREGVNAKTQAILNSLPEGLKKSKSTTKPT

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ACEN01000117
EMBL· GenBank· DDBJ
EEG32358.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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