C0DZY8 · C0DZY8_9CORY

Function

function

Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site2-6substrate
Binding site51substrate
Site51Transition state stabilizer
Binding site126substrate
Binding site181substrate
Binding site304substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionuroporphyrinogen decarboxylase activity
Biological Processprotoporphyrinogen IX biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uroporphyrinogen decarboxylase
  • EC number
  • Short names
    UPD
    ; URO-D

Gene names

    • Name
      hemE
    • ORF names
      CORMATOL_00284

Organism names

Accessions

  • Primary accession
    C0DZY8

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain114-130Uroporphyrinogen decarboxylase (URO-D)

Sequence similarities

Belongs to the uroporphyrinogen decarboxylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    330
  • Mass (Da)
    35,464
  • Last updated
    2009-05-05 v1
  • Checksum
    08E483FE712DBC7C
MRQAGRSLPEYRQVRAGIDMLDSCFMPELLAEITLQPVRRHDVDAAILFSDIVVPLKAAGVDVEIVSGRGPVVAQPILSMSDVDKLPILDSDIDGVMAGIGIIIDNLTSSQALIGFAGAPFTLASYLVEGGPSRNHEKTKAMMHAQPETWHALMRKLTPTITHFLSMQISAGIDAMQLFDSWAGFLTERDYREYVLPYSTEIFAAIAGADIPRIHFGVGTGELLGAMSQAGADVTGVDWRVPLDVAARRIHHAVGPKSVQGNLDPALLCAGEEVVRAEVTRICAEADRAISAGHAIGHIFNLGHGVLPTTDPEMITRAVSLVHEITPPQI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ACEB01000003
EMBL· GenBank· DDBJ
EEG28234.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp