B9WZW7 · B9WZW7_EUPTI

Function

function

Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionfarnesyl-diphosphate farnesyltransferase activity
Molecular Functionsqualene synthase activity
Biological Processfarnesyl diphosphate metabolic process
Biological Processlipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Squalene synthase
  • EC number

Gene names

    • Name
      EtSS

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Malpighiales > Euphorbiaceae > Euphorbioideae > Euphorbieae > Euphorbia > Euphorbia subgen. Euphorbia > Euphorbia sect. Tirucalli

Accessions

  • Primary accession
    B9WZW7

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane386-406Helical

Keywords

  • Cellular component

Family & Domains

Sequence similarities

Belongs to the phytoene/squalene synthase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    411
  • Mass (Da)
    47,048
  • Last updated
    2009-04-14 v1
  • Checksum
    265DD223AF7917F5
MGSLGAILRHPDDFYPLLKLKMASKHAEKQIPAQPHWGFCYSMLHKVSRSFALVIQQLGTELRDAVCIFYLVLRALDTVEDDTSIPTDVKVPILIAFHKHIYDREWHFSCGTKDYKVLMDQFHHVSTAFLELGKSYQEAIENITKRMGAGMAKFICKEVETVDDYDEYCHYVAGLVGLGLSKLFYASGSEDLAPDHLSNSMGLFLQKTNIIRDYLEDINEIPKSRMFWPRQIWSKYVNKLEDLKYEENSVKAVQCLNDMVTNALIHMDDCLKYMSALRDPAIFRFCGIPQIMAIGTLALCYNNIEVFRGVVKMRRGLTAKVIDRTRTMADVYRAFFDFSCMMKSKVDRNDPNAEKTLNRLEAVQKTCKDSGMLNKRKSYINGSNPIYNSALLVLLFVVLAVIVAYLNKQTN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB433916
EMBL· GenBank· DDBJ
BAH23428.1
EMBL· GenBank· DDBJ
mRNA
AB433917
EMBL· GenBank· DDBJ
BAH23429.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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