B9WZW7 · B9WZW7_EUPTI
- ProteinSqualene synthase
- GeneEtSS
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids411 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.
Catalytic activity
- 2 (2E,6E)-farnesyl diphosphate + NADH + H+ = squalene + 2 diphosphate + NAD+
Cofactor
Pathway
Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | farnesyl-diphosphate farnesyltransferase activity | |
Molecular Function | squalene synthase activity | |
Biological Process | farnesyl diphosphate metabolic process | |
Biological Process | lipid biosynthetic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSqualene synthase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Malpighiales > Euphorbiaceae > Euphorbioideae > Euphorbieae > Euphorbia > Euphorbia subgen. Euphorbia > Euphorbia sect. Tirucalli
Accessions
- Primary accessionB9WZW7
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 386-406 | Helical | |||
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length411
- Mass (Da)47,048
- Last updated2009-04-14 v1
- Checksum265DD223AF7917F5
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB433916 EMBL· GenBank· DDBJ | BAH23428.1 EMBL· GenBank· DDBJ | mRNA | ||
AB433917 EMBL· GenBank· DDBJ | BAH23429.1 EMBL· GenBank· DDBJ | Genomic DNA |