B9K7U7 · B9K7U7_THENN

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site6-9ATP (UniProtKB | ChEBI)
Binding site49ATP (UniProtKB | ChEBI)
Binding site53ATP (UniProtKB | ChEBI)
Binding site66UMP (UniProtKB | ChEBI)
Binding site127-134UMP (UniProtKB | ChEBI)
Binding site154ATP (UniProtKB | ChEBI)
Binding site160ATP (UniProtKB | ChEBI)
Binding site163ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • Ordered locus names
      CTN_0854

Organism names

Accessions

  • Primary accession
    B9K7U7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-208Aspartate/glutamate/uridylate kinase

Sequence similarities

Belongs to the UMP kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    231
  • Mass (Da)
    25,529
  • Last updated
    2009-03-24 v1
  • Checksum
    74378B2FCCE9C349
MRVLVKLSGEALSGEGRKGFDPERVSYLTSEIKKVVEEGYRVGIVVGAGNLFRGIELRGLSRERADQIGLLGTVMNAVYLKDHFEREGLKTKIFSQIVNLPDVESVSYDSIESAIENGFVLIFAGGTSNPFFTTDTAAVLRAKEMKAQIIVKATKVDGIYDKDPKRFSDARKIERLTFSEAMKMRIEVMDAEAFALCKKLGITVRVINFFEPGSLLRALKGENIGSIVLPD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000916
EMBL· GenBank· DDBJ
ACM23030.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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