B9DGY1 · AB1K7_ARATH
- ProteinProtein ACTIVITY OF BC1 COMPLEX KINASE 7, chloroplastic
- GeneABC1K7
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids695 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Involved in resistance to oxidative stress. Influences responses to reactive oxygen species (ROS) production. Regulates plastoglobules formation in thylakoids. Together with OSA1, regulates iron distribution within the chloroplast and mediates the oxidative stress response (PubMed:24117441).
Together with ABC1K8, influences chloroplast lipid synthesis/accumulation and modulates chloroplast membrane composition in response to stress (PubMed:25809944).
Together with ABC1K8, influences chloroplast lipid synthesis/accumulation and modulates chloroplast membrane composition in response to stress (PubMed:25809944).
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 265-273 | ATP (UniProtKB | ChEBI) | |||
Binding site | 287 | ATP (UniProtKB | ChEBI) | |||
Active site | 421 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast thylakoid membrane | |
Cellular Component | plastoglobule | |
Molecular Function | ATP binding | |
Molecular Function | histone H2AS1 kinase activity | |
Molecular Function | protein kinase activity | |
Molecular Function | protein serine kinase activity | |
Biological Process | cellular response to oxidative stress | |
Biological Process | membrane lipid biosynthetic process | |
Biological Process | phosphorylation | |
Biological Process | regulation of response to reactive oxygen species | |
Biological Process | response to iron ion starvation | |
Biological Process | response to oxidative stress |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein ACTIVITY OF BC1 COMPLEX KINASE 7, chloroplastic
- EC number
- Short namesABC1-LIKE KINASE 7
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionB9DGY1
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Plastid, chloroplast thylakoid membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 633-653 | Helical | |||
Transmembrane | 659-679 | Helical | |||
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Larger plastoglobules associated with thylakoids characterized by VTE1 accumulation and high tocopherol content. The pale green double mutant atsia1 atosa1 accumulates ferritin and superoxides, exhibits an increased nonphotochemical quenching (NPQ), and have a reduced tolerance to reactive oxygen species (ROS) (PubMed:24117441).
Lower levels of the highly unsaturated lipid digalactosyldiacylglycerol (DGDG) and of different forms of monogalactosyldiacylglycerol (MGDG) and kaempferol. The abc1k7 abc1k8 double mutant accumulates strong levels of oxylipin-conjugated MGDG and DGDG (PubMed:25809944).
Lower levels of the highly unsaturated lipid digalactosyldiacylglycerol (DGDG) and of different forms of monogalactosyldiacylglycerol (MGDG) and kaempferol. The abc1k7 abc1k8 double mutant accumulates strong levels of oxylipin-conjugated MGDG and DGDG (PubMed:25809944).
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 16 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain, transit peptide.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000441256 | ?-695 | Protein ACTIVITY OF BC1 COMPLEX KINASE 7, chloroplastic | ||
Transit peptide | 1-? | Chloroplast | |||
Proteomic databases
PTM databases
Expression
Tissue specificity
Mostly expressed in leaves and flowers, and, to a lower extent, in roots.
Induction
Down-regulated in response to iron deprivation.
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 259-589 | Protein kinase | |||
Sequence similarities
Belongs to the protein kinase superfamily. ADCK protein kinase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length695
- Mass (Da)78,279
- Last updated2009-03-24 v1
- ChecksumA701A309F5A500C4
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F4JFM1 | F4JFM1_ARATH | SIA1 | 724 |
Sequence caution
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Sequence conflict | 2 | in Ref. 5; AAM67100 | |||
Sequence conflict | 178 | in Ref. 3; AAL10497 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC009176 EMBL· GenBank· DDBJ | AAF13088.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AC013483 EMBL· GenBank· DDBJ | AAF21180.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002686 EMBL· GenBank· DDBJ | AEE74588.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002686 EMBL· GenBank· DDBJ | AEE74589.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002686 EMBL· GenBank· DDBJ | ANM65268.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY056806 EMBL· GenBank· DDBJ | AAL10497.1 EMBL· GenBank· DDBJ | mRNA | ||
AY080823 EMBL· GenBank· DDBJ | AAL87300.1 EMBL· GenBank· DDBJ | mRNA | ||
AK317324 EMBL· GenBank· DDBJ | BAH19998.1 EMBL· GenBank· DDBJ | mRNA | ||
AY088788 EMBL· GenBank· DDBJ | AAM67100.1 EMBL· GenBank· DDBJ | mRNA |