B8ZUX8 · NTPP_MYCLB
- ProteinNucleoside triphosphate pyrophosphatase
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids213 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Catalytic activity
- a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-phosphate + diphosphate + H+
Cofactor
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 79 | Proton acceptor | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | nucleoside triphosphate diphosphatase activity | |
Biological Process | nucleotide metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNucleoside triphosphate pyrophosphatase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium
Accessions
- Primary accessionB8ZUX8
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000146295 | 1-213 | Nucleoside triphosphate pyrophosphatase | |||
Sequence: MTRLVLGSASAGRLKVLRQAGIDPLVAASGVDEDLVTAGLGSDTSPRDVVSTLARAKATQVAAALSHAVADDCVVISCDSQLSIDGRLYGKPQSVANARQQWQSMAGRAGQLYTGHCVIRLLNNETTYSVDETSMTTICFGNPSAEDLEAYLACGESLQVAGGFTLDGLGGWFIDAVYGDPSTVVGIGLPLTRSLLSRAGLSIAAMWAANPVI |
Structure
Sequence
- Sequence statusComplete
- Length213
- Mass (Da)22,061
- Last updated2009-03-03 v1
- ChecksumA73A44F881A329D0
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FM211192 EMBL· GenBank· DDBJ | CAR70823.1 EMBL· GenBank· DDBJ | Genomic DNA |