B8ZS08 · PPK1_MYCLB

Function

function

Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

1739100200300400500600700
Type
IDPosition(s)Description
Binding site87ATP (UniProtKB | ChEBI)
Binding site428Mg2+ (UniProtKB | ChEBI)
Binding site458Mg2+ (UniProtKB | ChEBI)
Active site488Phosphohistidine intermediate
Binding site521ATP (UniProtKB | ChEBI)
Binding site621ATP (UniProtKB | ChEBI)
Binding site649ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentpolyphosphate kinase complex
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpolyphosphate kinase activity
Biological Processphosphorylation
Biological Processpolyphosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyphosphate kinase
  • EC number
  • Alternative names
    • ATP-polyphosphate phosphotransferase
    • Polyphosphoric acid kinase

Gene names

    • Name
      ppk
    • Ordered locus names
      MLBr01681

Organism names

Accessions

  • Primary accession
    B8ZS08

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001334051-739Polyphosphate kinase

Post-translational modification

An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.

Keywords

Structure

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region22-45Disordered
Compositional bias30-45Polar residues
Region714-739Disordered

Sequence similarities

Belongs to the polyphosphate kinase 1 (PPK1) family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    739
  • Mass (Da)
    83,288
  • Last updated
    2009-03-03 v1
  • Checksum
    21B5C61834DFBED5
MMSNDLLVTDIEAEARTEENIWHSDNSALAAPPAATTSASQDQLPDDRYLNRESSWLDFNARVLALAADNSLPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMDLSVRSADGLTPREQLSRIGEQTQWIASRHARVFLDSVLPALGEEGIYIVTWTDLDQAERDQLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVKQPEDGTQHFARVKVPNNVDRFVELANRGAVRDTSAGDEGQLIHRFLPMEELIAAFLPVLFPGTEIVEHHAFRITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDMTESMLELLLRELDVHPSDVIEVPGLLDLSSLWQIYGLDRPALKDRAFIPDTHPAFAERETPKSIFATLREGDVLVHHPYHSFATSVQRFIEQATADPDVLAIKQTLYRTSGDSPIVLALIEAAEAGKQVVALVEIKARFDEQANIRWARALEHAGVHVVYGIVGLKTHCKTCLVVRREGPTIRRYCHIGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLAYRNLLVAPYGIRRGIIERVEREVAAHRESGPQTGKGLIRLKMNALVDEQVIDALYRASQAGVRVEVVVRGICALRPGTEGFSENIFVRSILGRFLEHSRIIHFRAIDEFWIGSADMMHRNLDRRVEVLAQVKDSRLTAQLDELLKSALDPFTRCWELRPDGQWTASPQKGQQVRDHQESLMERHRSR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias30-45Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FM211192
EMBL· GenBank· DDBJ
CAR71776.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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