B8XIA9 · B8XIA9_EQUAR

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

135350100150200250300350
TypeIDPosition(s)Description
Binding site67Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site81Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site168Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site182Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site187a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Encoded on

  • Mitochondrion

Organism names

Accessions

  • Primary accession
    B8XIA9

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-36Helical
Transmembrane62-84Helical
Transmembrane96-119Helical
Transmembrane126-152Helical
Transmembrane164-185Helical
Transmembrane206-231Helical
Transmembrane274-293Helical
Transmembrane305-325Helical
Transmembrane331-350Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-195Cytochrome b/b6 N-terminal region profile
Domain196-353Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    353
  • Mass (Da)
    39,639
  • Last updated
    2009-03-03 v1
  • MD5 Checksum
    75571BFC2C3D6D1A022633B3B9123D41
HLIDYPTPSNLSYWWGFGSLAGLCLVIQMITGVLLAQHYTPHVDLAFHSVEHIMRDVRGGWLLRYMHANGASMFFMVVYLHIFRGLYYGSYISPREFVWCLGVVIFLLMIVTAFIGYVLPWGQMSFWGATVITSLASAIPIVGDTIVTWLWGGFSVDNATLTRFFSLHYLFPFIIAGASLIHLAALHQYGSNNPLGIHSSVDKIAFYPYIYVKDLVGWVAFAIFFSLWLFYAPNVLGHPDNYIPANPMSTPAHIVPEWYFLPIYAILRSIPDKLGGVVAIGLVFISLLALPFIDTNAVRSSSFRLINQRLFWVLLADCLLLGWIGCQPVEAPYVTIGQMASGVFFLYFAITPI

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue353

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ376600
EMBL· GenBank· DDBJ
ACL35773.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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