B8XA40 · ZFPS_SOLHA

Function

function

Specifically forms (2Z,6Z)-farnesyl diphosphate (Z,Z-FPP) from dimethylallyl diphosphate (DMAPP) and isopentenyl diphosphate (IPP). Also able to use nerylpyrophosphate (NPP) as substrate. Involved in the biosynthesis of several sesquiterpenes.

Catalytic activity

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
10 μMdimethylallyl diphosphate in the presence of 35 uM isopentenyl diphosphate
35 μMdimethylallyl diphosphate in the presence of 210 uM isopentenyl diphosphate
10 μMnerylpyrophosphate in the presence of 180 uM isopentenyl diphosphate
isopentenyl diphosphate acts as activator of its own catalysis.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site86

GO annotations

AspectTerm
Cellular Componentchloroplast stroma
Molecular Function2-cis,6-cis-farnesyl pyrophosphate synthase activity
Molecular Functiondehydrodolichyl diphosphate synthase activity
Molecular Functionmagnesium ion binding
Molecular Functionpolyprenyltransferase activity
Biological Processplastid membrane organization
Biological Processpolyprenol biosynthetic process
Biological Processresponse to cold

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic
  • EC number
  • Alternative names
    • Z,Z-FPP synthase
    • Z,Z-farnesyl pyrophosphate synthase

Gene names

    • Name
      ZFPS

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Solanales > Solanaceae > Solanoideae > Solaneae > Solanum > Solanum subgen. Lycopersicon

Accessions

  • Primary accession
    B8XA40

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for transit peptide, chain.

TypeIDPosition(s)Description
Transit peptide1-45Chloroplast
ChainPRO_000040511946-303(2Z,6Z)-farnesyl diphosphate synthase, chloroplastic

Family & Domains

Sequence similarities

Belongs to the UPP synthetase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    303
  • Mass (Da)
    34,430
  • Last updated
    2009-03-03 v1
  • Checksum
    C9289E0BC89193BE
MSSLVLQCWKLSSPSLILQQNTSISMGAFKGIHKLQIPNSPLTVSARGLNKISCSLSLQTEKLCYEDNDNDLDEELMPKHIALIMDGNRRWAKDKGLDVSEGHKHLFPKLKEICDISSKLGIQVITAFAFSTENWKRAKGEVDFLMQMFEELYDEFSRSGVRVSIIGCKTDLPMTLQKCIALTEETTKGNKGLHLVIALNYGGYYDILQATKSIVNKAMNGLLDVEDINKNLFDQELESKCPNPDLLIRTGGDQRVSNFLLWQLAYTEFYFTKTLFPDFGEEDLKEAIINFQQRHRRFGGHTY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ194969
EMBL· GenBank· DDBJ
ACJ38408.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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