B8NC58 · MEP1_ASPFN

Function

function

Secreted metalloproteinase that allows assimilation of proteinaceous substrates.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

163550100150200250300350400450500550600
Type
IDPosition(s)Description
Binding site430Zn2+ (UniProtKB | ChEBI); catalytic
Active site431
Binding site434Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentextracellular space
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Extracellular metalloproteinase mep
  • EC number
  • Alternative names
    • Elastinolytic metalloproteinase mep
    • Fungalysin mep

Gene names

    • Name
      mep
    • ORF names
      AFLA_038530

Organism names

Accessions

  • Primary accession
    B8NC58

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, propeptide, chain, glycosylation.

Type
IDPosition(s)Description
Signal1-19
PropeptidePRO_000040715420-246
ChainPRO_0000407155247-635Extracellular metalloproteinase mep
Glycosylation287N-linked (GlcNAc...) asparagine

Keywords

PTM databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region.

Type
IDPosition(s)Description
Compositional bias290-310Polar residues
Region290-311Disordered

Sequence similarities

Belongs to the peptidase M36 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    635
  • Mass (Da)
    69,302
  • Last updated
    2009-03-03 v1
  • Checksum
    7AACCD32E8409C2C
MMRGLLLAGALGLPLAVLAHPTHHAHGLQRRTVDLNSFRLHQAAKYINATESSSDVSSSFSPFTEQSYVETATQLVKNILPDATFRVVKDHYIGSNGVAHVNFRQTAHGLDIDNADFNVNVGKNGKIFSYGHSFYTGKIPDANPLTKRDYTDPVAALRGTNEALQLSITLDQVSTEATEDKESFNFKGVSGTVSDPKAQLVYLVKEDGSLALTWKVETDIDSNWLLTYIDANTGKDVHGVVDYVAEADYQVYAWGINDPTEGPRTVISDPWDSSASAFTWISDGENNYTTTRGNNGIAQSNPTGGSQYLKNYRPDSPDLKFQYPYSLNATPPESYIDASITQLFYTANTYHDLLYTLGFNEEAGNFQYDNNGKGGAGNDYVILNAQDGSGTNNANFATPPDGQPGRMRMYIWTESQPYRDGSFEAGIVIHEYTHGLSNRLTGGPANSRCLNALESGGMGEGWGDFMATAIRLKAGDTHSTDYTMGEWAANKKGGIRAYPFSTSLETNPLTYTSLNELDEVHAIGAVWANVLYELLWNLIDKHGKNDGPKPEFKDGVPTDGKYLAMKLVIDGMALQPCNPNCVQARDAILDADKALTDGANKCEIWKAFAKRGLGEGAEYHASRRVGSDKVPSDAC

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias290-310Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EQ963476
EMBL· GenBank· DDBJ
EED52152.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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