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B8JFS8 · SYY_ANAD2

Function

function

Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).

Catalytic activity

Features

Showing features for binding site.

142050100150200250300350400
TypeIDPosition(s)Description
Binding site33L-tyrosine (UniProtKB | ChEBI)
Binding site167L-tyrosine (UniProtKB | ChEBI)
Binding site171L-tyrosine (UniProtKB | ChEBI)
Binding site230ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionRNA binding
Molecular Functiontyrosine-tRNA ligase activity
Biological Processtyrosyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tyrosine--tRNA ligase
  • EC number
  • Alternative names
    • Tyrosyl-tRNA synthetase
      (TyrRS
      )

Gene names

    • Name
      tyrS
    • Ordered locus names
      A2cp1_1171

Organism names

Accessions

  • Primary accession
    B8JFS8

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001892551-420Tyrosine--tRNA ligase

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Features

Showing features for motif, domain.

Type
IDPosition(s)Description
Motif38-47'HIGH' region
Motif227-231'KMSKS' region
Domain353-419S4 RNA-binding

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    420
  • Mass (Da)
    45,319
  • Last updated
    2009-03-03 v1
  • MD5 Checksum
    FBE4EA701A4EB92E9D881C21403A7397
MQNLLEALVSRSLVHDQTPGLQARLAQGPITGYVGFDPTADSLHVGHLLAVMSLAWLQRCGGTPIIVVGGGTGMVGDPSGKRSERPVLSVEEIDRNVAAIRAQLERFVSFEGQNAARVRNNADWLRAIGLMEFLRDVGKHFTVNYMLAKDSVKGRMESGISFTEFSYQLIQAYDFWHLFRSEKCELQMGGSDQWGNITAGAELVSRKDGASVHGLTFPLLTTASGTKFGKTEGGAVWLDPARTSPYKFFQFWLNTDDRDVERLLKFFTFLSVEEIAALLAEQARDPGKRPAQRRLAEDVTARVHGPDVTRSVVEASRILFGGTDLRAASADVLEVLAGEIPSATVTGDELAALTVADLLVKVGLAASKGEVRRGVAGRGFSLNGAVLESGDAKVAAGDLLAGGYALLQKGKRNYALVKVR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001359
EMBL· GenBank· DDBJ
ACL64516.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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