B8J8E6 · B8J8E6_ANAD2

Function

function

Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

146250100150200250300350400450
TypeIDPosition(s)Description
Binding site118-124ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUDP-N-acetylmuramoylalanine-D-glutamate ligase activity
Biological Processcell division
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-N-acetylmuramoylalanine--D-glutamate ligase
  • EC number
  • Alternative names
    • D-glutamic acid-adding enzyme
    • UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase

Gene names

    • Name
      murD
    • Ordered locus names
      A2cp1_3909

Organism names

Accessions

  • Primary accession
    B8J8E6

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain116-300Mur ligase central
Domain322-437Mur ligase C-terminal

Sequence similarities

Belongs to the MurCDEF family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    462
  • Mass (Da)
    48,294
  • Last updated
    2009-03-03 v1
  • Checksum
    DD0EB5DA23791151
MAAPDLKGTRVTVVGLAKSGVAAARLCAREGARVTVTDRRGEAELGGALAALPASVTRHLGGHDPADFTGAELVVASPGVPLANPEIQEARRRGVAVWGEVELAARFLGGLPIVGITGTNGKSTTTALTGALLARDRRTFVGGNLGTPLSELVLSGEPADAAVVELSSFQLEGIERFRARVAAVLNVTPDHLDRYPDVDAYAAAKARLFATQQPDDVAVANARDPRALAMAGASRADLHTFGFGAPTPASARDEGGEPGPEGTAIWFTPRGRAPERYQLRNRALRGRHNRENAMAAVLCARLMGVPGEAVQAGLDAFPGLHHRLELVAEGRGVEWVNDSKATNVDSTFVGLAAFPSGAPRVVLIMGGRGKKAPYAPLRPLFGGRVKALLTIGEDAPAIERELGDLAPTEPCGDLADAVRRAAVLSGPGDVVLLSPACASYDQFANYEERGEAFRRLATEQAR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001359
EMBL· GenBank· DDBJ
ACL67232.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp