B8IZ81 · B8IZ81_DESDA

Function

function

Catalyzes the biosynthesis of agmatine from arginine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site505Proton donor

GO annotations

AspectTerm
Molecular Functionarginine decarboxylase activity
Molecular Functionmetal ion binding
Biological Processarginine catabolic process
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biosynthetic arginine decarboxylase
  • EC number
  • Short names
    ADC

Gene names

    • Name
      speA
    • Ordered locus names
      Ddes_0901

Organism names

Accessions

  • Primary accession
    B8IZ81

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue106N6-(pyridoxal phosphate)lysine

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain80-348Orn/DAP/Arg decarboxylase 2 N-terminal
Domain376-453Arginine decarboxylase helical bundle
Domain583-636Arginine decarboxylase C-terminal helical

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    638
  • Mass (Da)
    72,071
  • Last updated
    2009-03-03 v1
  • Checksum
    842BB998312F6602
MAKNRALQQWRVEDSIELYGIRNWGAGYFDVSDAGEVVICPQGPKGPQVSIPEIISGLRDRGYDMPVLLRVENILDSRIANIHESFRKAIKNLGYTGAYRGVFPIKVNQQQQVVEKIAQFGAQYHHGLEVGSKAELIAAVSLMQDREACIVCNGYKDEEFMDLGLQALRMGFNVFFVLEMPSELNVLLERSKALGVRPNIGVRAKLAVKAGGHWTDSGGERSTFGLSPAQVVDVVDTLKSHDMLDCFKLLHYHLGSQVSNIRDIRTGVMEGARLYVGLIQEGAPMGYLDLGGGLAVDYDGSHTNFISSRNYNLDEYCTDVVETIMSILDEENVPHPHIITESGRATVAYYSVLLFNVLDVSMIEEVQLPESLPEGMPEPVQNLRETLANISLRNLQECYNDAIYYRDEMRQLFSTGRVNLRQRTIAERFFWAIIMRIAQEKTRLKNVPRDLADIDVSLADIYYGNFSVFQSLPDTWAIDQLFPVMPIHRLREFPARHAIISDITCDSDGRIDQFIDPQGMKPTLELHPLRDGEEYYLGVFLVGAYQETLGDLHNLMGDTNVVSIRVAEDGSYEYVREIRGDSVADILSYVEYDPRRILEDLRSTAELAVRQGRISPSERFSVMQAFEDGLRGYTYFER

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001358
EMBL· GenBank· DDBJ
ACL48808.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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