B8I447 · ACKA_RUMCH

Function

function

Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Mg2+. Can also accept Mn2+.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.

Features

Showing features for binding site, active site, site.

TypeIDPosition(s)Description
Binding site7Mg2+ (UniProtKB | ChEBI)
Binding site14ATP (UniProtKB | ChEBI)
Binding site91substrate
Active site148Proton donor/acceptor
Site180Transition state stabilizer
Binding site208-212ATP (UniProtKB | ChEBI)
Site241Transition state stabilizer
Binding site283-285ATP (UniProtKB | ChEBI)
Binding site331-335ATP (UniProtKB | ChEBI)
Binding site384Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionacetate kinase activity
Molecular FunctionATP binding
Molecular Functionmagnesium ion binding
Biological Processacetyl-CoA biosynthetic process
Biological Processorganic acid metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acetate kinase
  • EC number
  • Alternative names
    • Acetokinase

Gene names

    • Name
      ackA
    • Ordered locus names
      Ccel_2136

Organism names

Accessions

  • Primary accession
    B8I447

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001167971-397Acetate kinase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the acetokinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    397
  • Mass (Da)
    43,226
  • Last updated
    2009-03-03 v1
  • Checksum
    E8A15216EF32ECA2
MKVLVINAGSSSLKYQLIDMKNETVLAKGLCDRIGIDNSFIKQSRGSEEAVILNKELKNHKDAIEAVISALTDDNMGVIKNMSEISAVGHRIVHGGEKFNSSVVIDENVMNAVRECIDVAPLHNPPNIIGIEACQQIMPNIPMVAVFDTTFHSSMPDYAYLYALPYELYEKYGIRKYGFHGTSHKYVAERASAMLDKSLNELKIITCHLGNGSSICAVNKGKSIDTSMGFTPLQGLAMGTRSGTIDPEVVTFLMEKENLDVKGVSKLLNKKSGVLGISGVSSDFRDLHAAADAGNSRAELAIEIFCYGVKKFIGEYIAVMNGVDAIVFTAGVGENNSVVRNMIISDMDFLGIKIDEEKNKLRGQEVDISTADAAVRTLVIPTNEELAIARETVRLVK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001348
EMBL· GenBank· DDBJ
ACL76480.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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