B8I164 · METAA_RUMCH

Function

function

Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-acetyl-L-homoserine from L-homoserine: step 1/1.

Features

Showing features for site, active site, binding site.

130620406080100120140160180200220240260280300
TypeIDPosition(s)Description
Site111Important for acyl-CoA specificity
Active site142Acyl-thioester intermediate
Binding site163substrate
Binding site192substrate
Site192Important for substrate specificity
Active site235Proton acceptor
Active site237
Binding site249substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functionhomoserine O-acetyltransferase activity
Molecular Functionhomoserine O-succinyltransferase activity
Biological ProcessL-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Homoserine O-acetyltransferase
  • EC number
  • Short names
    HAT
  • Alternative names
    • Homoserine transacetylase
      (HTA
      )

Gene names

    • Name
      metAA
    • Ordered locus names
      Ccel_3331

Organism names

Accessions

  • Primary accession
    B8I164

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001911811-306Homoserine O-acetyltransferase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the MetA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    306
  • Mass (Da)
    35,726
  • Last updated
    2009-03-03 v1
  • Checksum
    69B156268823C6C3
MPIRIPDNLPAVEILNSENIFVMSEDRAYHQDIRPLKIAILNIMPTKITTETQLLRLLGNTPIQVEIILLRPASHLSKNTPEEHLETFYKTFDEVQREHFDGLIITGAPVEQMPFEDVNYWEELKQIMDWSKKNVYSTLHICWGAQAGLYYHYGVPKRDLPKKVFGVFEHNKIKEHVKLLRGFDDIFFVPHSRHTEVTHEDVAKIDDLEILAESKEAGVYLVASKDGRHIFATGHSEYDPYTLKFEYERDLEKGLDIEVPKNYFPGDDPAKEPIVRWRGHGNLLFLNWLNYYVYQETPYDLTNIGK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001348
EMBL· GenBank· DDBJ
ACL77620.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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