B8EJU5 · B8EJU5_METSB

Function

function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site69FMN (UniProtKB | ChEBI)
Active site99Proton donor
Binding site138FMN (UniProtKB | ChEBI)
Binding site168FMN (UniProtKB | ChEBI)
Binding site223-224FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionRNA binding
Molecular FunctiontRNA dihydrouridine synthase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-dihydrouridine synthase
  • EC number

Gene names

    • Ordered locus names
      Msil_0527

Organism names

Accessions

  • Primary accession
    B8EJU5

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain14-308DUS-like FMN-binding

Sequence similarities

Belongs to the dus family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    327
  • Mass (Da)
    34,545
  • Last updated
    2009-03-03 v1
  • Checksum
    A619E55017592ECF
MRIGSVALPGCAFLAPMSGVTDIAMRRVAQRFGASLVFTEMVAAEAYAKGDAENRLKAEGRGVDPHVVQIAGCDAQSMARAARIAADSGAAILDINMGCPAKKVINGYSGSHLMRDLPLALDLIRATVRAVDIPVTLKMRLGWDEASINAAELGRLAEAEGIAMLTVHGRTRSQFYNGKADWRAIRAVKEAVSIPVVANGDCASLADAARMMDVSGADAVMIGRAAIGQPWLVGMIAERLATGVVGAEPSPAEKSEAAQEHYDGVLRLFGREQGMRHARKHLAAYAERSGSPAAGALRARLVTADDPETVRSILSELFDFPLRAEAA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001280
EMBL· GenBank· DDBJ
ACK49499.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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