B8EJU5 · B8EJU5_METSB
- ProteintRNA-dihydrouridine synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids327 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
Catalytic activity
- a 5,6-dihydrouridine in tRNA + NAD+ = a uridine in tRNA + NADH + H+
- a 5,6-dihydrouridine in tRNA + NADP+ = a uridine in tRNA + NADPH + H+
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 69 | FMN (UniProtKB | ChEBI) | |||
Active site | 99 | Proton donor | |||
Binding site | 138 | FMN (UniProtKB | ChEBI) | |||
Binding site | 168 | FMN (UniProtKB | ChEBI) | |||
Binding site | 223-224 | FMN (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | RNA binding | |
Molecular Function | tRNA dihydrouridine synthase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-dihydrouridine synthase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Beijerinckiaceae > Methylocella
Accessions
- Primary accessionB8EJU5
Proteomes
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length327
- Mass (Da)34,545
- Last updated2009-03-03 v1
- ChecksumA619E55017592ECF
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001280 EMBL· GenBank· DDBJ | ACK49499.1 EMBL· GenBank· DDBJ | Genomic DNA |