B8EIS2 · ACKA_METSB

Function

function

Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Mg2+. Can also accept Mn2+.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.

Features

Showing features for binding site, active site, site.

TypeIDPosition(s)Description
Binding site9Mg2+ (UniProtKB | ChEBI)
Binding site16ATP (UniProtKB | ChEBI)
Binding site100substrate
Active site157Proton donor/acceptor
Site188Transition state stabilizer
Binding site215-219ATP (UniProtKB | ChEBI)
Site248Transition state stabilizer
Binding site290-292ATP (UniProtKB | ChEBI)
Binding site335-339ATP (UniProtKB | ChEBI)
Binding site386Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionacetate kinase activity
Molecular FunctionATP binding
Molecular Functionmagnesium ion binding
Biological Processacetyl-CoA biosynthetic process
Biological Processorganic acid metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acetate kinase
  • EC number
  • Alternative names
    • Acetokinase

Gene names

    • Name
      ackA
    • Ordered locus names
      Msil_2978

Organism names

Accessions

  • Primary accession
    B8EIS2

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001168051-404Acetate kinase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the acetokinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    404
  • Mass (Da)
    44,380
  • Last updated
    2009-03-03 v1
  • Checksum
    12E52999A1AA7A44
MSRCVITLNAGSSSIKFALFREGLTQEGSAKELTPMAIGLAEMVGEERRITVHDGAGAKIYEVKRTEHVDAPFHAEALRRILAWRQSAFPDAEVVAAGHRVVHGGVHYSAPVIVTDEVLKYLHTLIPLAPLHEPYNIAGILGAREAWPHVEQVACFDTAFHRTHPFVNDVFALPRRFYDEGVRRYGFHGLSYEYIVRRLREIAPLHAAGRVVVAHLGNGASMCAIRDGLSVASSMGFTALDGLPMGTRCGQLDPGVVLYLMQEKKMSAAEITDLLYRESGLKGLSGLSHDMRELEAADTLEAQQAIEYFVFRIRRELGGLAAVLKGIDAIVFCGGIGENSRHVRERVLEGMEWIGVELDRSANSANAEVISSERSRTRVFVIPTDEEGMIARHTLALLDQMAAA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001280
EMBL· GenBank· DDBJ
ACK51889.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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