B8EI85 · B8EI85_METSB

Function

function

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

Catalytic activity

Features

Showing features for active site.

116120406080100120140160
TypeIDPosition(s)Description
Active site51Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionthioredoxin peroxidase activity
Biological Processcell redox homeostasis
Biological Processcellular response to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    thioredoxin-dependent peroxiredoxin
  • EC number
  • Alternative names
    • Bacterioferritin comigratory protein
    • Thioredoxin peroxidase
    • Thioredoxin-dependent peroxiredoxin Bcp

Gene names

    • Ordered locus names
      Msil_1619

Organism names

Accessions

  • Primary accession
    B8EI85

Proteomes

Subcellular Location

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-23Disordered
Domain9-161Thioredoxin

Sequence similarities

Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    161
  • Mass (Da)
    17,428
  • Last updated
    2009-03-03 v1
  • Checksum
    44FFE9F04A8B0905
MTRAAGGKCEPGMAAPEFKLPGDRGEPISLQSFKGRKLVLYFYPKDDTSGCTKEAIDFNQLKPEFEKAGAAILGVSPDTVASHVKFKTKHQLGLDLASDESKAMLGAYGVWVEKSMYGRKYMGVERTTLLIDRQGVIAQIWSKVKVPGHAEAVLAAAKALP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001280
EMBL· GenBank· DDBJ
ACK50567.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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