B8E001 · KITH_DICTD
- ProteinThymidine kinase
- Genetdk
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids198 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + thymidine = ADP + dTMP + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 16-23 | ATP (UniProtKB | ChEBI) | ||||
Sequence: GGMYSGKS | ||||||
Binding site | 89-92 | ATP (UniProtKB | ChEBI) | ||||
Sequence: EEGQ | ||||||
Active site | 90 | Proton acceptor | ||||
Sequence: E | ||||||
Binding site | 146 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 149 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 184 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 187 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | thymidine kinase activity | |
Molecular Function | zinc ion binding | |
Biological Process | DNA biosynthetic process | |
Biological Process | thymidine metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameThymidine kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Dictyoglomota > Dictyoglomia > Dictyoglomales > Dictyoglomaceae > Dictyoglomus
Accessions
- Primary accessionB8E001
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000117666 | 1-198 | Thymidine kinase | |||
Sequence: MEIVSGASGWIEVICGGMYSGKSEELIRRVRRAQIAKQKVQVFKHSLDIRYDKDYVASHTGLKIEAIPVSSSADIERLVKDDTQVVAIEEGQFFDMGLVKVCQRLADRGKRVIVAGLDQDFRGEPFGPMPYLMAVAEYVDKLHAICMKCGNVASRTQRIIDGKPAYYDDPIILVGAFETYEARCRHCHVVLRREEDEK |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length198
- Mass (Da)22,341
- Last updated2009-03-03 v1
- Checksum05561B8A57BBDAB1
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001251 EMBL· GenBank· DDBJ | ACK42084.1 EMBL· GenBank· DDBJ | Genomic DNA |