B7ZD10 · B7ZD10_DANRE
- ProteinDual specificity protein phosphatase
- Genesi:ch211-223p8.8
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids186 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.
Catalytic activity
- H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 126 | Phosphocysteine intermediate | ||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | membrane | |
Molecular Function | MAP kinase phosphatase activity | |
Molecular Function | myosin phosphatase activity | |
Molecular Function | protein tyrosine phosphatase activity | |
Molecular Function | protein tyrosine/serine/threonine phosphatase activity | |
Biological Process | negative regulation of MAPK cascade |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDual specificity protein phosphatase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionB7ZD10
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 134-154 | Helical | ||||
Sequence: AALVLAYLMIYCNFSLVDAIL |
Keywords
- Cellular component
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 33-181 | Tyrosine-protein phosphatase | ||||
Sequence: NHVDEVWPNLFLGDMYMSHDRYGLWSLGVTHVLNAAHGKMCCKGNDDYYGTTVKYYGVPANDLPTFDISPFFYPSAQYIHDALSTTGAKVFVHCAVGMSRSAALVLAYLMIYCNFSLVDAILKVKERRWIFPNRGFLKQLITLDNELKL | ||||||
Domain | 102-160 | Tyrosine specific protein phosphatases | ||||
Sequence: PFFYPSAQYIHDALSTTGAKVFVHCAVGMSRSAALVLAYLMIYCNFSLVDAILKVKERR |
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length186
- Mass (Da)20,928
- Last updated2009-03-03 v1
- Checksum57A32CE6E991307A
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL929005 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |