B7ZD10 · B7ZD10_DANRE

Function

function

Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site126Phosphocysteine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentmembrane
Molecular FunctionMAP kinase phosphatase activity
Molecular Functionmyosin phosphatase activity
Molecular Functionprotein tyrosine phosphatase activity
Molecular Functionprotein tyrosine/serine/threonine phosphatase activity
Biological Processnegative regulation of MAPK cascade

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dual specificity protein phosphatase
  • EC number

Gene names

    • Name
      si:ch211-223p8.8

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    B7ZD10
  • Secondary accessions
    • A0A8M1NRN1

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane134-154Helical

Keywords

  • Cellular component

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain33-181Tyrosine-protein phosphatase
Domain102-160Tyrosine specific protein phosphatases

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    186
  • Mass (Da)
    20,928
  • Last updated
    2009-03-03 v1
  • Checksum
    57A32CE6E991307A
MEDTDQILDNVLHKSPTIEELEGILHGGQLSCNHVDEVWPNLFLGDMYMSHDRYGLWSLGVTHVLNAAHGKMCCKGNDDYYGTTVKYYGVPANDLPTFDISPFFYPSAQYIHDALSTTGAKVFVHCAVGMSRSAALVLAYLMIYCNFSLVDAILKVKERRWIFPNRGFLKQLITLDNELKLQGTSN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL929005
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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